Lentiviral Solutions - Recent Publications

>2019

Al-Khadairi, G., et al. (2019). PRAME promotes epithelial-to-mesenchymal transition in triple negative breast cancer. Journal of Translational Medicine doi: 10.1186/s12967-018-1757-3 [Lentifect™ Lentiviral particles expressing PRAME]
Nayak, R.C., et al. (2019). The signaling axis atypical protein kinase C λ/ι-Satb2 mediates leukemic transformation of B-cell progenitors. Nature Comunications doi: 10.1038/s41467-018-07846-y [OMICSLINK™ Satb2, Evt3 lentiviral ORF expression clones]
Shen, X. and Cheng, J. (2019). Effects of MDR1 (C3435T) Polymorphism on Resistance, Uptake, and Efflux to Antiepileptic Drugs. DNA and Cell Biology doi: 10.1089/dna.2018.4553 [Lenti-Pac™ lentiviral packaging kit]
Liang, R., et al. (2019). Long noncoding RNA DNAJC3‐AS1 promotes osteosarcoma progression via its sense‐cognate gene DNAJC3. Cancer Medicine doi: 10.1002/cam4.1955 [OMICSLINK™ DNAJC-AS1 lentiviral ORF expression clone]
Wang, L., et al. (2019). GLRX inhibition enhances the effects of geftinib in EGFR-TKI-resistant NSCLC cells through FoxM1 signaling pathway. Journal of Cancer Research and Clinical Oncology doi: 10.1007/s00432-019-02845-y [Lentifect™ Lentiviral particles expressing FoxM1]
Song, N., et al. (2019). Knockdown of high mobility group box 3 impairs cell viability and colony formation but increases apoptosis in A549 human non‑small cell lung cancer cells. Oncology eports doi: 10.3892/ol.2019.9927 [OMICSLINK™ HMGB lentiviral shRNA clone set]
Jiang, Z., et al. (2019). Rpn10 promotes tumor progression by regulating hypoxia-inducible factor 1 alpha through the PTEN/Akt signaling pathway in hepatocellular carcinoma. Cancer Letters doi: 10.1016/j.canlet.2019.01.020 [OMICSLINK™ Rpn10 lentiviral shRNA clone set]
Zhao, Y-S., et al. (2019). MiR-182-5p Knockdown Targeting PTEN Inhibits Cell Proliferation and Invasion of Breast Cancer Cells. Yonsei Medical Journal doi: 10.3349/ymj.2019.60.2.148 [miArrest™ miR-182-5p lentiviral inhibitor clone]
Chen, Y., et al. (2019). Thermal stress induces glycolytic beige fat formation via a myogenic state. Nature doi:10.1038/s41586-018-0801-z [OMICSLINK™ Gabpa, Erra, Errg lentiviral ORF expression clones; OMICSLINK™ Gabpa lentiviral shRNA clone set]
Wang, W., et al. (2019). Inhibition of cardiac allograft rejection in mice using interleukin‐35‐modified mesenchymal stem cells. Scandinavian Journa of Immunology doi: 10.1111/sji.12750 [OMICSLINK™ IL-35 lentiviral ORF expression clone]
Shen, Y., et al. (2019). Loss-of-function mutations in QRICH2 cause male infertility with multiple morphological abnormalities of the sperm flagella. Nature Communications doi:10.1038/s41467-018-08182-x [OMICSLINK™ QRICH2 lentiviral shRNA clone set]
Siddiqui, A., et al. (2019). Thymidylate synthase maintains the de-differentiated state of triple negative breast cancers. Cell Death & Differentiation doi: 10.1038/s41418-019-0289-6 [OMICSLINK™ TS lentiviral ORF expression clone]
Vázquez-Domínguez, I., et al. (2019). Downregulation of specific FBXW7 isoforms with differential effects in T-cell lymphoblastic lymphoma. Oncogene doi: 10.1038/s41388-019-0746-1 [OMICSLINK™ FBXW7 lentiviral ORF expression clones]
Goldberg, S., et al. (2019). Cysteine engineered fibronectin type III domain binding molecules. United States Patent Applicaiton 10/196,446 [OMICSLINK™ HGF lentiviral ORF expression clone]
Goldberg, S., et al. (2019). Cysteine engineered fibronectin type III domain binding molecules. United States Patent Applicaiton 14/512,801 [OMICSLINK™ HGF lentiviral ORF expression clone; Lenti-Pac™ lentiviral packaging kit]
Aird, D., et al. (2019). Sensitivity to splicing modulation of BCL2 family genes defines cancer therapeutic strategies for splicing modulators. Nature Communications doi:10.1038/s41467-018-08150-5 [Lenti-Pac™ lentiviral packaging kit]
Goncalves, M.B., et al. (2019). Regulation of myelination by exosome associated retinoic acid release from NG2-positive cells. The Journal of Neuroscience doi: 10.1523/JNEUROSCI.2922-18.2019 [Lentifect™ Lentiviral particles]
Jiao, J-X., et al. (2019). Knockdown of aristaless-like homeobox1 inhibits epithelial-mesenchymal transition through Wnt/β-catenin signaling pathway in melanoma cells. Biochemical and Biophysical Research Communications doi: 10.1016/j.bbrc.2019.02.050 [OMICSLINK™ ALX1 lentiviral shRNA clone set]
Wei, F., et al. (2019). PD-L1 promotes colorectal cancer stem cell expansion by activating HMGA1-dependent signaling pathways. Cancer Letters doi: 10.1016/j.canlet.2019.02.022 [OMICSLINK™ PD-1, PD-L1, HMGA1 lentiviral ORF expression clones; OMICSLINK™ HMGA1 lentiviral shRNA clone set]
Yoon, J-H, et al. (2019). Error-Prone Replication through UV Lesions by DNA Polymerase θ Protects against Skin Cancers. Cell doi: 10.1016/j.cell.2019.01.023 [Lentifect™ Lentiviral particles expressing SV40 large T antigen]
Qin, Y., et al. (2019). CCL18 promotes the metastasis of squamous cell carcinoma of the head and neck through MTDH‐NF‐κB signalling pathway. Journal of Cellular and Molecular Medicine doi: 10.1111/jcmm.14168 [Lentifect™ Lentiviral particles expressing shRNA targeting MTDH]
Zhou, X., et al. (2019). Inhibition of MEK suppresses hepatocellular carcinoma growth through independent MYC and BIM regulation. Cellular Oncology doi: 10.1007/s13402-019-00432-4 [Lentifect™ Lentiviral particles expressing MYC antigen]
Yang, Y., et al. (2019). MiR-135 suppresses glycolysis and promotes pancreatic cancer cell adaptation to metabolic stress by targeting phosphofructokinase-1. Nature Communications doi: 10.1038/s41467-019-08759-01 [miExpress™ miR-135a lentiviral precursor clone; miArrest™ miR-135a lentiviral inhibitor clone]
Zhou, J., et al. (2019). Glycerol kinase 5 confers gefitinib resistance through SREBP1/SCD1 signaling pathway. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-019-1057-7 [Lentifect™ Lentiviral particles expressing GK5, SCD1]
Liu, S., et al. (2019). S1PR1 regulates the switch of two angiogenic modes by VE-cadherin phosphorylation in breast cancer. Cell Death & Disease doi: 10.1038/s41419-019-1411-x [Lenti-Pac™ lentiviral packaging kit]
Pushpavathi, G., et al. (2019). CRISPR/Cas9 Editing of Glia Maturation Factor Regulates Mitochondrial Dynamics by Attenuation of the NRF2/HO-1 Dependent Ferritin Activation in Glial Cells. Journal of Neuroimmune Pharmacology doi: 10.1007/s11481-019-09833-6 [GeneHero™ lentiviral sgRNA clones]
Celikkaya, H., et al. (2019). GATA3 Promotes the Neural Progenitor State but Not Neurogenesis in 3D Traumatic Injury Model of Primary Human Cortical Astrocytes. Frontiers in Cellular Neuroscience doi: 10.3389/fncel.2019.00023 [OMICSLINK™ GATA3 lentiviral ORF expression clone]
Lin, K., et al. (2019). Mammalian Pum1 and Pum2 Control Body Size via Translational Regulation of the Cell Cycle Inhibitor Cdkn1b. Cell Reports doi: 10.1016/j.celrep.2019.01.111 [Lenti-Pac™ lentiviral packaging kit]
Jie, L., et al. (2019). Autophagy exerts pivotal roles in regulatory effects of 1α,25-(OH)2D3 on the osteoclastogenesis. Biochemical and Biophysical Research Communications doi: 10.1016/j.bbrc.2019.02.114 [OMICSLINK™ Beclin1, Atg7 and Atg5 lentiviral ORF expression clones]
Li, M., et al. (2019). Suppressor gene GRHL1 is associated with prognosis in patients with oesophageal squamous cell carcinoma. Oncology Letters doi: 10.3892/ol.2019.10072 [OMICSLINK™ GRHL1 lentiviral ORF expression clone]
Wu, G., et al. (2019). METHOD FOR ESTABLISHING EUKARYOTIC EXPRESSION CELL LINE OF CD36 MUTANT GENE THAT ENCODES CD36 DEFICIENCY. United States Patent Application 16/188,187 [Lenti-Pac™ lentiviral packaging kit]
Xu, C., et al. (2019). Differentiation roadmap of embryonic Sertoli cells derived from mouse embryonic stem cells. Stem Cell Research & Therapy doi: 10.1186/s13287-019-1180-6 [Lenti-Pac™ concentration solution]
Sun, Y-J., et al. (2019). Therapeutic hypothermia protects photoreceptors through activating Cirbp pathway. Neurochemistry Journal doi: 10.1016/j.neuint.2019.03.006 [OMICSLINK™ Cirbp lentiviral ORF expression clone]
Guan, C., et al. (2019). MMP-12 regulates proliferation of mouse macrophages via the ERK/P38 MAPK pathways during inflammation. Experimental Cell Research doi: 10.1016/j.yexcr.2019.03.018 [OMICSLINK™ MMP12-1, MMP12-2 lentiviral shRNA clone sets; Lenti-Pac™ lentiviral packaging kit]
Ni, F., et al. (2019). Ptpn21 Controls Hematopoietic Stem Cell Homeostasis and Biomechanics. Cell Stem Cell doi: 10.1016/j.stem.2019.02.009 [OMICSLINK™ Ptpn21 wil type and mutant lentiviral ORF expression clones; Lenti-Pac™ lentiviral packaging kit]
Zheng, H., et al. (2019). MicroRNA-181a/b-1 over-expression enhances osteogenesis by modulating PTEN/PI3K/AKT signaling and mitochondrial metabolism. Bone doi: 10.1016/j.bone.2019.03.020 [OMICSLINK™ PTEN lentiviral ORF expression clone]
Ning, Y., et al. (2019). CK2-mediated CCDC106 phosphorylation is required for p53 degradation in cancer progression. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-019-1137-8 [Lentifect™ Lentiviral particles expressing shRNA targeting CCDC106]
Fang, L., et al. (2019). Targeting late-stage non-small cell lung cancer with a combination of DNT cellular therapy and PD-1 checkpoint blockade. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-019-1126-y [OMICSLINK™ PD-L1 lentiviral ORF expression clone]
Cuce, M., et al. (2019). Trabectedin triggers direct and NK-mediated cytotoxicity in multiple myeloma. Journal of Hematology & Oncology doi: 10.1186/s13045-019-0714-9 [Lenti-Pac™ lentiviral packaging kit]
Zhang, B., et al. (2019). Proton pump inhibitor pantoprazole inhibits gastric cancer metastasis via suppression of telomerase reverse transcriptase gene expression. Cancer Letters doi: 10.1016/j.canlet.2019.03.029 [OMICSLINK™ hTERT lentiviral ORF expression clone]
Cassaletto, J.B., et al. (2019). MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM. Proceedings of the National Academy of Sciences of the United States of America doi: 10.1073/pnas.1819085116 [Lentifect™ Lentiviral particles expressing HGF]
Cai, Z., et al. (2019). Immunoglobulin‑like transcript 4 and human leukocyte antigen‑G interaction promotes the progression of human colorectal cancer. International Journal of Oncology doi: 10.3892/ijo.2019.4761 [OMICSLINK™ ILT4 lentiviral ORF expression clone]
Dinamarca, M.C., et al. (2019). Complex formation of APP with GABAB receptors links axonal trafficking to amyloidogenic processing. Nature Communications doi: 10.1038/s41467-019-09164-3 [Lentifect™ Lentiviral particles expressing GB1a, GB1b]
Shen, W., et al. (2019). MicroRNA-101-5p inhibits the growth and metastasis of cervical cancer cell by inhibiting CXCL6. European Review for Medical and Pharmacological Sciences 2019; 23: 1957-1968 [Lenti-Pac™ lentiviral packaging kit]
Dakhama, A., et al. (2019). Tollip Inhibits ST2 Signaling in Airway Epithelial Cells Exposed to Type 2 Cytokines and Rhinovirus. Journal of Innate Immunity doi: 10.1159/000497072 [OMICSLINK™ Tollp, IRAK1 lentiviral shRNA clone sets; Lenti-Pac™ lentiviral packaging kit]
Xiang, Y., et al. (2019).Cx32 exerts anti-apoptotic and pro-tumor effects via the epidermal growth factor receptor pathway in hepatocellular carcinoma. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-019-1142-y [OMICSLINK™ Cx32 lentiviral ORF expression clone]
Warren, C.S., et al. (2019). EXAMINING THE MARKERS OF VITAMIN C CYTOTOXICITY IN PANCREATIC DUCTAL ADENOCARCINOMA. Masters Thesis, The UNiversity of British Columbia [Lentifect™ Lentiviral particles expressing KRAS wild type and G12D mutant; Lenti-Pac™ lentiviral packaging kit]
Ma, Q., et al. (2019). ENKUR Is Involved in the Regulationof Cellular Biology in Colorectal CancerCells via PI3K/Akt Signaling Pathway. Technology in Cancer Research & Treatment doi: 10.1177/1533033819841433 [OMICSLINK™ lentiviral shRNA clone set targeting EUNKUR; Lenti-Pac™ lentiviral packaging kit]
Moore, S., et al. (2019). ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD. Acta Neuropathologica doi:10.1007/s00401-019-01999-w [OMICSLINK™ ADAR2 wild type and mutant lentiviral ORFexpression clones]
Han, J., et al. (2019). Characterization of Distinct Populations of Carcinoma-Associated Fibroblasts from Non–Small Cell Lung Carcinoma Reveals a Role for ST8SIA2 in Cancer Cell Invasion. Neoplasia doi: 10.1016/j.neo.2019.03.009 [OMICSLINK™ ST8SAI2 lentiviral ORFexpression clone]
Ma, X., et al. (2019). Identification of Tumor Specific Peptide as EpCAM Ligand and Its Potential Diagnostic and Therapeutic Clinical Application. Molecular Pharmacutics doi: 10.1021/acs.molpharmaceut.9b00185 [Lentifect™ Lentiviral particles expressing luciferase]

>2018

Anorga, S., et al. (2018). Deregulation of Hippo – TAZ pathway during renal injury confers a fibrotic maladaptive phenotype. FASEB Journal doi: 10.1096/fj.201700722R [OMICSLINK™ TAZ lentiviral ORF expression clone]
Kenney, R.M., et al. (2018). A pH-Sensing Optode for Mapping Spatiotemporal Gradients in 3D Paper-Based Cell Cultures. Analytical Chemistry doi: 10.1021/acs.analchem.7b05015 [Lentiviral particles expressing mCherry]
Smith, S.R., et al. (2018). The phosphatase PPM1A controls monocyte-to-macrophage differentiation. Scientific Reports doi: 10.1038/s41598-017-18832-7 [GLuc-ON™ PPM1A lentiviral promoter-reporter clone]
Hosaka, K., et al. (2018). Dual roles of endothelial FGF-2–FGFR1–PDGF-BB and perivascular FGF-2–FGFR2–PDGFRβ signaling pathways in tumor vascular remodeling. Cell Discovery doi: 10.1038/s41421-017-0002-1 [Fgf2 lentiviral shRNA clone set; Lenti-Pac™ lentiviral packaging kit]
Xiaobo, Y., et al. (2018). Pyruvate Kinase M2 Modulates the Glycolysis of Chondrocyte and Extracellular Matrix in Osteoarthritis. DNA and Cell Biology doi: 10.1089/dna.2017.4048 [OMICSLINK™ PKM2 ORF lentiviral expression clone]
Zang, X., et al. (2018). MAEL contributes to gastric cancer progression by promoting ILKAP degradation. Oncotarget doi: 10.18632/oncotarget.22970 [Lentifect™ purified lentiviral particles expressing shRNA targeting MAEL]
Cao, M-Q., et al. (2018). miR-182-5p promotes hepatocellular carcinoma progression by repressing FOXO3a. Journal of Hematology & Oncolog doi: 10.1186/s13045-018-0555-y [miExpress™ miR-182-5p miRNA lentiviral precursor clone; miArrest™ miR-182-5p miRNA lentiviral inhibitor clone; Lenti-Pac™ lentiviral packaging kit]
Liang, S., et al. (2018). The lncRNA XIST interacts with miR-140/miR-124/iASPP axis to promote pancreatic carcinoma growth. Oncotarget doi: 10.18632/oncotarget.22555 [Lenti-Pac™ lentivirus concentration kit]
Borges, L., et al. (2018). SLAMF1 ANTAGONISTS AND USES THEREOF . United States Patent Application 20180016555 [OMICSLINK™ SLAMF1 ORF lentiviral expression clone]
Kim, J., et al. (2018). Ubiquitin C decrement plays a pivotal role in replicative senescence of bone marrow mesenchymal stromal cells. Cell Death & Disease doi: 10.1038/s41419-017-0032-5 [OMICSLINK™ UBC ORF lentiviral expression clone]
Fort, R.S., et al. (2018). Nc886 is epigenetically repressed in prostate cancer and acts as a tumor suppressor through the inhibition of cell growth. BMC Cancer doi: 10.1186/s12885-018-4049-7 [miExpress™ nc886 lentiviral miRNA precursor clone]
Britain, C.M., et al. (2018). Sialylation of EGFR by the ST6Gal-I sialyltransferase promotes EGFR activation and resistance to gefitinib-mediated cell death. Journal of Ovarian Research doi: 10.1186/s13048-018-0385-0 [Lentifect™ purified lentiviral particles expressing ST6Gal-I]
Hai, L., et al. (2018). Notch1 is a prognostic factor that is distinctly activated in the classical and proneural subtype of glioblastoma and that promotes glioma cell survival via the NF-κB(p65) pathway. Cell Death & Disease doi: 10.1038/s41419-017-0119-z [Lentifect™ purified lentiviral particles expressing shRNA targeting Notch1]
Wang, J., et al. (2018). Targeting dual specificity protein kinase TTK attenuates tumorigenesis of glioblastoma. Oncotarget doi: 10.18632/oncotarget.23152 [Lentifect™ purified lentiviral particles expressing shRNA targeting TTK]
Xiong, J., et al. (2018). A Metabolic Basis for Endothelial-to-Mesenchymal Transition. Molecular Cell doi: 10.1016/j.molcel.2018.01.010 [OMICSLINK™ CPT1A and SMAD7 lentiviral ORF expression clones]
Yuan, G., et al. (2018). Flavagline analog FL3 induces cell cycle arrest in urothelial carcinoma cell of the bladder by inhibiting the Akt/PHB interaction to activate the GADD45α pathway. Journal of Experimental and Clinical Cancer Research doi: 10.1186/s13046-018-0695-5 [Lenti-Pac™ lentiviral packaging kit]
Mu, N., et al. (2018). PRL- 3 is a potential glioblastoma prognostic marker and promotes glioblastoma progression by enhancing MMP7 through the ERK and JNK pathways. Theranostics doi: 10.7150/ thno .22699 [Lentifect™ purified lentiviral particles expressing sh-PRL-3]
Maier, M., et al. (2018). The Role of Trio, a Rho Guanine Nucleotide Exchange Factor, in Glomerular Podocytes. International Journal of Molecular Sciences doi: 10.3390/ijms19020479 [GeneHero™ lentiviral clone expressing sgRNA targeting Trio]
Al-Kharash, L.A., et al. (2018). The DNA methyl-transferase protein DNMT1 enhances tumor-promoting properties of breast stromal fibroblasts. Oncotarget doi:10.18632/oncotarget.23411 [OMICSLINK™ DNMT1 lentiviral ORF expression clone]
Fesler, A., et al. (2018). Modified miR-15a has therapeutic potential for improving treatment of advanced stage colorectal cancer through inhibition of BCL2, BMI1, YAP1 and DCLK1. Oncotarget doi: 10.18632/oncotarget.23414 [Lenti-Pac™ lentiviral packaging kit]
Zhang, Z., and Wu, W-S. (2018). Application of TALE-Based Approach for Dissecting Functional MicroRNA-302/367 in Cellular Reprogramming. MicroRNA Protocols doi: 10.1007/978-1-4939-7601-0_21 [Lenti-Pac™ lentiviral packaging kit]
Karakashev, S., et al. (2018). CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity. Nature Communications doi: 10.1038/s41467-018-03031-3 [Lenti-Pac™ lentiviral packaging kit]
Lin, C., et al. (2018). NIT1 suppresses tumour proliferation by activating the TGFβ1–Smad2/3 signalling pathway in colorectal cancer. Cell death & Disease doi: 10.1038/s41419-018-0333-3 [OMICSLINK™ NIT1 lentiviral ORF expression clone]
Qiang, Y-Y., et al. (2018).Along with its favorable prognostic role, CLCA2 inhibits growth and metastasis of nasopharyngeal carcinoma cells via inhibition of FAK/ERK signaling. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-018-0692-8 [OMICSLINK™ CLCA2 lentiviral ORF expression clone]
Jiang, L., et al. (2018). Brain Renin–Angiotensin System Blockade Attenuates Methamphetamine-Induced Hyperlocomotion and Neurotoxicity. Neurotherapeutics doi: 10.1007/s13311-018-0613-8 [Lenti-Pac™ lentiviral packaging kit]
Li, N., et al. (2018). The role of BKCa in endometrial cancer HEC-1-B cell proliferation and migration. Gene doi: 10.1016/j.gene.2018.02.055 [OMICSLINK™ BKCa lentiviral shRNA clone set]
Yang, Y-F., et al. (2018). A positive feedback loop of IL-17B-IL-17RB activates ERK/β-catenin to promote lung cancer metastasis. Cancer Letters doi: 10.1016/j.canlet.2018.02.037 [OMICSLINK™ IL-17RB lentiviral ORF expression clone]
Ali, M.M., et al. (2018). PAN-cancer analysis of S-phase enriched lncRNAs identifies oncogenic drivers and biomarkers. Nature Communications doi: 10.1038/s41467-018-03265-1 [Lentiviral particles expressing shRNA targeting SCAT7]
Clark, P.M., et al. (2018). Novel and Haplotype Specific MicroRNAs Encoded by the Major Histocompatibility Complex. Scientific Reports doi: 10.1038/s41598-018-19427-6 [OMICSLINK™ DICER1 lentiviral shRNA clone set]
Liu, Y., et al. (2018). MicroRNA-214 Suppresses Ovarian Cancer by Targeting β-Catenin. Cellular Physiology and Biochemistry doi: 10.1159/000487733 [miExpress™ miR-214 lentiviral precursor clone]
Dong, L., et al. (2018). USP27-mediated Cyclin E stabilization drives cell cycle progression and hepatocellular tumorigenesis. Oncogene doi: 10.1038/s41388-018-0137-z [OMICSLINK™ USP27 lentiviral shRNA clone set]
Liu, Y., et al. (2018). A comprehensive function analysis of LMO2 in different breast cancer subtypes. Oncotarget doi: 10.18632/oncotarget.23542 [OMICSLINK™ LMO2 lentiviral ORF expression clone; Lenti-Pac™ lentiviral packaging kit]
Xin, H., et al. (2018). Chemokine CXCL3 mediates prostate cancer cells proliferation, migration and gene expression changes in an autocrine/paracrine fashion. International Urology and Nephrology doi: 10.1007/s11255-018-1818-9 [Lenti-Pac™ lentiviral packaging kit]
Aquino, J.G.C. and Pacheco, B.A.S. (2018). Compartmentalized method of nucleic acid delivery and compositions and uses thereof. Unites States Patent Application US20180055997A1 [Lenti-Pac™ lentiviral packaging kit]
Zhu, R., et al. (2018). Toll-like receptor 3 modulates the behavioral effects of cocaine in mice. Journal of Neuroinflammation doi: 10.1186/s12974-018-1130-8 [OMICSLINK™ TLR3 lentiviral ORF expression clone]
Xion, F., et al. (2018). Orthotopic hepatic cancer: radiofrequency hyperthermia-enhanced intratumoral herpes simplex virus-thymidine kinase gene therapy. Oncotarget doi: 10.18632/oncotarget.23586 [Lentiviral particles expressing luciferase and RFP]
Brasil, S., et al. (2018). New perspectives for pharmacological chaperoning treatment in methylmalonic aciduria cblB type. BBA – Molecular Basis of Disease doi: 10.1016/j.bbadis.2017.11.024 [OMICSLINK™ ATR lentiviral ORF expression clone]
Chen, X., et al. (2018). Radiotherapy-induced cell death activates paracrine HMGB1-TLR2 signaling and accelerates pancreatic carcinoma metastasis. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-018-0726-2 [Lenti-Pac™ lentiviral packaging kit]
Fiorillo, M., et al. (2018). Bergamot natural products eradicate cancer stem cells (CSCs) by targeting mevalonate, Rho-GDI-signalling and mitochondrial metabolism. Biochimica et Biophysica Acta (BBA) – Bioenergetics doi: 10.1016/j.bbabio.2018.03.018 [OMICSLINK™ lentiviral ORF expression clones; Lenti-Pac™ lentiviral packaging kit]
Wang, X., et al. (2018). Reciprocal Signaling between Glioblastoma Stem Cells and Differentiated Tumor Cells Promotes Malignant Progression. Cell Stem Cell doi: 10.1016/j.stem.2018.03.011 [OMICSLINK™ VGF, BDNF lentiviral ORF expression clones]
Roy, L., et al. (2018). CD133 Promotes Adhesion to the Ovarian Cancer Metastatic Niche. Cancer Growth and Metastasis doi: 10.1177/1179064418767882 [OMICSLINK™ PROM1 lentiviral ORF expression clone]
Subburayan, K., et al. (2018). Par-4-dependent p53 up-regulation plays a critical role in thymoquinone-induced cellular senescence in human malignant glioma cells. Cancer Letters doi: 10.1016/j.canlet.2018.04.009 [Lenti-Pac™ 293a packaging cells]
Oh, H.J., et al. (2018). Klotho plays a protective role against glomerular hypertrophy in a cell cycle-dependent manner in diabetic nephropathy. American Journal of Physiology-Renal Physiology doi: 10.1152/ajprenal.00462.2017 [OMICSLINK™ Klotho lentiviral ORF expression clone; Lenti-Pac™ lentiviral packaging kit]
Zhang, B., et al. (2018). TSPAN15 interacts with BTRC to promote oesophageal squamous cell carcinoma metastasis via activating NF-κB signaling. Nature Communications doi: 10.1038/s41467-018-03716-9 [OMICSLINK™ TSPAN15 lentiviral ORF expression clone; OMICSLINK™ TSPAN15 lentiviral shRNA clone set]
Yang, Q., et al. (2018). Metformin Enhances the Effect of Regorafenib and Inhibits Recurrence and Metastasis of Hepatic Carcinoma After Liver Resection via Regulating Expression of Hypoxia Inducible Factors 2α (HIF-2α) and 30 kDa HIV Tat-Interacting Protein (TIP30). Medical Sciences Monitor doi: 10.12659/MSM.906687 [Lenti-Pac™ lentiviral packaging kit]
Tang, Y., et al. (2018). The fructose – 2,6 – bisphosphatase TIGAR suppresses NF – κ B signaling by directly inhibiting the linear ubiquitin assembly complex LUBAC. The Journal of Biological Chemistry doi: 10.1074/jbc.RA118.002727 [OMICSLINK™ TIGAR lentiviral ORF expression clone]
Clouston, H.M., et al. (2018). Effect of Tissue Factor on Colorectal Cancer Stem Cells. Anticancer Research May 2018 vol. 38 no. 5 2635-2642 [OMICSLINK™ TF lentiviral ORF expression clone; Lenti-Pac™ lentiviral packaging kit]
Qi, Y., et al. (2018). High C-X-C motif chemokine 5 expression is associated with malignant phenotypes of prostate cancer cells via autocrine and paracrine pathways. International Journal of Oncology doi: 10.3892/ijo.2018.4388 [OMICSLINK™ CXCL5 lentiviral ORF expression clone; Lenti-Pac™ lentiviral packaging kit]
Yu, j., et al. (2018). Epigenetic silencing of miR-483-3p promotes acquired gefitinib resistance and EMT in EGFR-mutant NSCLC by targeting integrin β3. Oncogene doi: 10.1038/s41388-018-0276-2 [Lentiviral particles expressing integrin β3]
Chen, L., et al. (2018). HCC-derived exosomes elicit HCC progression and recurrence by epithelial-mesenchymal transition through MAPK/ERK signalling pathway. Cell Death & Disease doi: 10.1038/s41419-018-0534-9 [Lenti-Pac™ lentiviral packaging kit]
Rakeda, K., et al. (2018). Activation of p70S6 Kinase‐1 in Mesenchymal Stem Cells Is Essential to Lung Tissue Repair. Sem Cells Translational Medicine doi: 10.1002/sctm.17-0200 [OMICSLINK™ p70S6k1 lentiviral ORF expression clone; Lenti-Pac™ lentiviral packaging kit]
Jackson, T.C., et al. (2018). Acute Physiology and Neurologic Outcomes after Brain Injury in SCOP/PHLPP1 KO Mice. Scientific Reports doi: 10.1038/s41598-018-25371-2 [OMICSLINK™ SCOP/PHLPP1 lentiviral ORF expression clone; Lenti-Pac™ lentiviral packaging kit]
Yang, T., et al. (2018). Brain ischemic preconditioning protects against ischemic injury and preserves the blood-brain barrier via oxidative signaling and Nrf2 activation. Redox Biology doi: 10.1016/j.redox.2018.05.001 [GLuc-ON™ Nrf2 lentiviral promoter-reporter clone]
Chen, Y-C., et al. (2018). ATOH1/RFX1/RFX3 transcription factors facilitate the differentiation and characterisation of inner ear hair cell-like cells from patient-specific induced pluripotent stem cells harbouring A8344G mutation of mitochondrial DNA. Cell Death & Disease doi: 10.1038/s41419-018-0488-y2 [OMICSLINK™ ATOH1 lentiviral ORF expression clone; GLuc-ON™ MYO7A lentiviral promoter-reporter clone]
Liu, H., et al. (2018). Downregulation of Glutathione S‑transferase A1 suppressed tumor growth and induced cell apoptosis in A549 cell line. Oncology Letters doi: 10.3892/ol.2018.8608 [Lentiviral particles expressing GSTA1 and shRNA against GSTA1]
Zhu, Z-R., et al. (2018). MiR-140-3p is Involved in In-Stent Restenosis by Targeting C-Myb and BCL-2 in Peripheral Artery Disease. Journal of Atherosclerosis and Thrombosis doi: 10.5551/jat.44024 [OMICSLINK™ C-Myb lentiviral ORF expression clone; Lenti-Pac™ lentiviral packaging kit]
Ottaviani, S., et al. (2018). TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression. Nature Communications doi: 10.1038/s41467-018-03962-x [OMICSLINK™ TGF-β lentiviral ORF expression clone]
Shen, Y., et al. (2018). TSPY1 suppresses USP7-mediated p53 function and promotes spermatogonial proliferation. Cell Death & Disease doi: 10.1038/s41419-018-0589-7 [OMICSLINK™ TSPY1, TSPY15 lentiviral ORF expression clones]
Cui, T., et al. (2018). DDB2 represses ovarian cancer cell dedifferentiation by suppressing ALDH1A1. Cell Death & Disease doi: 10.1038/s41419-018-0585-y [OMICSLINK™ DDB2 lentiviral ORF expression clone]
Rogers, S., et al. (2018). MASTL overexpression promotes chromosome instability and metastasis in breast cancer. Oncogene doi: 10.1038/s41388-018-0295-z [OMICSLINK™ MASTL lentiviral ORF expression clone]
Li, L., et al. (2018). Compounds and Compositions for Immunotherapy. United States Patent Application US20180110874A1 [OMICSLINK™ HER2 lentiviral ORF expression clone]
Yang, Z., et al. (2018). Knockdown of TNF‑α alleviates acute lung injury in rats with intestinal ischemia and reperfusion injury by upregulating IL‑10 expression. International Journal of Molecular Medicine doi: 10.3892/ijmm.2018.3674 [OMICSLINK™ TNF‑α lentiviral shRNA clone set; Lenti-Pac™ lentiviral packaging kit]
Li, X., et al. (2018). Sulfiredoxin-1 enhances cardiac progenitor cell survival against oxidative stress via the upregulation of the ERK/NRF2 signal pathway. Free Radical Biology and Medicine doi: 10.1016/j.freeradbiomed.2018.05.060 [OMICSLINK™ SRXN1 lentiviral ORF expression clone; OMICSLINK™ SRXN1 lentiviral shRNA clone set]
Tran, A.P., et al. (2018). Modulation of receptor protein tyrosine phosphatase sigma increases chondroitin sulfate proteoglycan degradation through Cathepsin B secretion to enhance axon outgrowth. The Journal of Neuroscience doi: 10.1523/JNEUROSCI.3214-17.2018 [Lentifect™ Lentiviral particles expressing Crystatin-B]
Talukdar, S., et al. (2018). MDA-9/Syntenin regulates protective autophagy in anoikis-resistant glioma stem cells. Proceedings of the National Academy of Sciences of the United States of America doi: 10.1073/pnas.1721650115 [OMICSLINK™ PKC-α lentiviral shRNA clone set]
Baumert, T., et al. (2018). CLINICAL GENE SIGNATURE-BASED HUMAN CELL CULTURE MODEL AND USES THEREOF. United States Patent Application 20180119096 [Lentifect™ Lentiviral particles expressing HDV, HBV]
Porello, A., et al. (2018). Factor XIIIA—expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking. Nature Communications doi: 10.1038/s41467-018-04355-w [Lentifect™ Lentiviral particles expressing CCL2, Factor 13; Lentifect™ Lentiviral particles expressing shRNA against Factor 13; OMICSLINK™ CCL2 lentiviral shRNA clone set]
Quan, Y., et al. (2018). Roseburia intestinalis-derived flagellin is a negative regulator of intestinal inflammation. Biochemical and Biophysical Research Communications doi: 10.1016/j.bbrc.2018.05.075 [Lenti-Pac™ lentiviral packaging kit]
Qiu, Q., et al. (2018). Gingipains disrupt F‐actin and cause osteoblast apoptosis via integrin β1. Journal of Periodontal Research doi: 10.1111/jre.12563 [OMICSLINK™ Itgb1 lentiviral ORF expression clone]
Wang, Y., et al. (2018). Exosomes derived from miR-214-enriched bone marrow-derived mesenchymal stem cells regulate oxidative damage in cardiac stem cells by targeting CaMKII. Oxidative Medicine and Cellular Longevity [OMICSLINK™ CaMKII lentiviral ORF expression clone]
Jiang, G., et al. (2018). IL‑17A and GDF15 are able to induce epithelial‑mesenchymal transition of lung epithelial cells in response to cigarette smoke. Experimental and Therapeutic Medicine doi: 10.3892/etm.2018.6145 [OMICSLINK™ GDF15 lentiviral ORF expression clone]
Li, J., et al. (2018). FFAR4 is involved in regulation of neurotensin release from neuroendocrine cells and male C57BL/6 mice. Endocrinology doi: 10.1210/en.2018-00284 [OMICSLINK™ FFAR4 lentiviral ORF expression clone]
Gibbs, K.L., et al. (2018). Inhibiting p38 MAPK alpha rescues axonal retrograde transport defects in a mouse model of ALS. Cell Death & Disease doi: 10.1038/s41419-018-0624-8 [OMICSLINK™ p38 MAPKα lentiviral shRNA clone set]
Glumac, P.M/, et al. (2018). The identification of a novel antibody for CD133 using human antibody phage display. The Prostate doi: 10.1002/pros.23656 [Lentifect™ Lentiviral particles expressing PROM1]
Jaiswal, A., et al. (2018). MicroRNA-99a mimics inhibit M1 macrophage phenotype and adipose tissue inflammation by targeting TNFα. Cellular & Molecular Immunology doi: 10.1038/s41423-018-0038-7 [miExpress™ miR-99a lentiviral precursor clone]
Liu, J., et al. (2018). m6A demethylase FTO facilitates tumor progression in lung squamous cell carcinoma by regulating MZF1 expression. Biochemical and Biophysical Research Communications doi: 10.1016/j.bbrc.2018.05.175 [OMICSLINK™ FTO lentiviral ORF expression clone; Lenti-Pac™ lentiviral packaging kit]
Bi, Q-J., et al. (2018). LHX6 inhibits the proliferation, invasion and migration of breast cancer cells by modulating the PI3K/Akt/mTOR signaling pathway. European Review for Medical and Pharmacological Sciences 2018; 22: 3067-3073 [Lentifect™ Lentiviral particles expressing LHX6]
Qian, H., et al. (2018). The lncRNA MIR4435-2HG promotes lung cancer progression by activating β-catenin signalling. Journal of Molecular Medicine doi: 10.1007/s00109-018-1654-5 [OMICSLINK™ MIR4435-2HG lentiviral shRNA clone set]
Lei, F.X., et al. (2018). RIP1 protects melanoma cells from apoptosis induced by BRAF/MEK inhibitors. Cell Death & Disease doi: 10.1038/s41419-018-0714-7 [OMICSLINK™ RIP1 lentiviral ORF expression clone]
Chen, J., et al. (2018). Protein kinase D1 regulates hypoxic metabolism through HIF-1α and glycolytic enzymes incancer cells. Oncology Reports doi: 10.3892/or.2018.6479 [OMICSLINK™ PKD1 lentiviral ORF expression clone]
Yan, Y., et al. (2018). Mesenchymal stem cell expression of interleukin-35 protects against ulcerative colitis by suppressing mucosal immune responses. Cytotherapy doi: 10.1016/j.jcyt.2018.05.004 [Lenti-Pac™ lentiviral packaging kit]
Wang, K., et al. (2018). Hypoxia-stressed cardiomyocytes promote early cardiac differentiation of cardiac stem cells through HIF-1α/Jagged1/Notch1 signaling. Acta Pharmaceutica Sinica B doi: 10.1016/j.apsb.2018.06.003 [Lentifect™ purified lentiviral particles expressing HIF-1α]
Kan, A., et al. (2018). ELTD1 Function in Hepatocellular Carcinoma is Carcinoma -Associated Fibroblast- Dependent. Journal of Cancer doi: 10.7150/ jca .24406 [OMICSLINK™ ELTD1 lentiviral ORF expression clone]
Yang, L., et al. (2018). AP -2 β inhibits hepatocellular carcinoma invasion and metastasis through Slug and Snail to suppress epithelial-mesenchymal transition. Theranostics doi: 10.7150/ thno .25166 [miExpress™ miR-27a lentiviral precursor clone; Lenti-Pac™ lentiviral packaging kit]
Koeck, I, et al. (2018). Tumor Necrosis Factor-α Initiates miRNA-mRNA Signaling Cascades in Obstruction-Induced Bladder Dysfunction. The American Journal of Pathology doi: 10.1016/j.ajpath.2018.05.008 [miExpress™ lentiviral precursor clones; miArrest™ lentiviral inhibitor clones]
Yang, D., et al. (2018). Utilization of adipocyte-derived lipids and enhanced intracellular trafficking of fatty acids contribute to breast cancer progression. Cell Communication and Signaling doi: 10.1186/s12964-018-0221-6 [OMICSLINK™ ATGL lentiviral shRNA clone set]
Bai, P-s., et al. (2018). Hepatitis B virus promotes proliferation and metastasis in male Chinese hepatocellular carcinoma patients through the LEF-1/miR-371a-5p/SRCIN1/pleiotrophin/Slug pathway. Experimental Cell Research doi: 10.1016/j.yexcr.2018.06.020 [Lentifect™ Lentiviral particles expressing miR-371a]
Estrada, C.C., et al. (2018). Krüppel-like factor 4 is a negative regulator of STAT3-induced glomerular epithelial cell proliferation. JCI Insight doi: 10.1172/jci.insight.98214 [OMICSLINK™ KLF4 lentiviral ORF expression clone; OMICSLINK™ KLF4 lentiviral shRNA clone set]
Dakhama, A. and Chu, H-W. (2018). The Use of CRISPR-Cas9 Technology to Reveal Important Aspects of Human Airway Biology. Type 2 Immunity doi: 10.1007/978-1-4939-7896-0_27 [Lentiviral CRISPR clones; Lenti-Pac™ lentiviral packaging kit]
Seeley, J.J., et al. (2018). Induction of innate immune memory via microRNA targeting of chromatin remodelling factors. Nature doi: 10.1038/s41586-018-0253-5 [miExpress™ miR-222, miR-146a lentiviral precursor clones; miArrest™ miR-222, miR-146a lentiviral inhibitor clones; Lenti-Pac™ lentiviral packaging kit]
Zheng, H., et al. (2018). MicroRNA-138 Inhibits Osteogenic Differentiation and Mineralization of Human Dedifferentiated Chondrocytes by Regulating RhoC and the Actin Cytoskeleton. JBMR Plus doi: 10.1002/jbm4.10071 [OMICSLINK™ RhoC ORF lentiviral expression clone]
Zou, Y., et al. (2018). Identification of proteins interacting with pORF5 in the pathogenesis of C. trachomatis. Am J Transl Res 2018;10(6):1633-1647 [Lenti-Pac™ lentiviral packaging kit]
Li, Y., et al. (2018). Histone H1 acetylation at lysine 85 regulates chromatin condensation and genome stability upon DNA damage, Nucleic Acids Research doi: 10.1093/nar/gky568 [Lentiviral CRISPR clones]
Rajan, S. and Panzade, G. (2018). miR-876-3p regulates glucose homeostasis and insulin sensitivity by targeting adiponectin. Journal of Endocrinology doi: 10.1530/JOE-17-0387 [miExpress™ miR-876-3p lentiviral precursor clone; miArrest™ miR-876-3p lentiviral inhibitor clone]
Zhang, M., et al. (2018). Thymoquinone induces apoptosis in bladder cancer cell via endoplasmic reticulum stress-dependent mitochondrial pathway. Chemico-Biological Interactions doi: 10.1016/j.cbi.2018.06.013 [OMICSLINK™ CHOP lentiviral shRNA clone set]
Kim, K. M., et al. (2018). SCAMP4 enhances the senescent cell secretome. Genes & Development doi: 10.1101/gad.313270.118 [Lentifect™ Lentiviral particles expressing SCAMP4-Myc]
Wang, K., et al. (2018). Hypoxia-stressed cardiomyocytes promote early cardiac differentiation of cardiac stem cells through HIF-1α/Jagged1/Notch1 signaling. Acta Pharmaceutica Sinica B doi: 10.1016/j.apsb.2018.06.003 [Lentifect™ Lentiviral particles expressing HIF-1α]
Li, L., et al. (2018). COMPOUNDS FOR TARGETED IMMUNOTHERAPY. United States Patent Application 20180177887 [OMICSLINK™ HER2 lentiviral ORF expression clone]
Qian, K., et al. (2018). Overexpression of Salusin-α Inhibits Vascular Intimal Hyperplasia in an Atherosclerotic Rabbit Model. BioMed Research International doi: 10.1155/2018/8973986 [OMICSLINK™ salusin-α lentiviral shRNA clone set; Lenti-Pac™ lentiviral packaging kit]
Zhang, C., et al. (2018). KLF5 controls glutathione metabolism to suppress p190-BCR- ABL+ B-cell lymphoblastic leukemia. Oncotarget doi: 10.18632/oncotarget.25667 [OMICSLINK™ hKLF5, mGstm1 lentiviral ORF expression clones]
Kalimuthu, S., et al. (2018). Migration of mesenchymal stem cells to tumor xenograft models and in vitro drug delivery by doxorubicin. International Journal of Medical Sciences doi: 10.7150/ijms.25760 [Lentifect™ Lentiviral particles expressing eGFP, mCherry, and Renilla luciferase]
Li, J., et al. (2018). Wild- type IDH2 promotes the Warburg effect and tumor growth through HIF1 α in lung cancer. Theranostics doi: 10.7150/ thno .21524 [OMICSLINK™ IDH2 lentiviral ORF expression clone]
Xiao, S., et al. (2018). Anti-inflammatory effect of hesperidin enhances chondrogenesis of human mesenchymal stem cells for cartilage tissue repair. Journal of Inflammation doi: 10.1186/s12950-018-0190-y [OMICSLINK™ p65 lentiviral ORF expression clone; OMICSLINK™ lentiviral shRNA clone sets for p65]
Takahashi, Y., et al. (2018). An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure. Nature Communications doi: 10.1038/s41467-018-05254-w [OMICSLINK™ MAP1LC3 lentiviral ORF expression clone]
Huang, X., et al. (2018). Adam12 and lnc015192 act as ceRNAs in breast cancer by regulating miR-34a. Oncogene doi: 10.1038/s41388-018-0410-1 [Lentifect™ Lentiviral particles expressing SIP3]
Song, X., et al. (2018). AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc– Activity. Current Biology doi: 10.1016/j.cub.2018.05.094 [OMICSLINK™ BECN1 lentiviral ORF expression clone]
Sun, X., et al. (2018). miR-451 elevation relieves inflammatory pain by suppressing microglial activation-evoked inflammatory response via targeting TLR4. Cell and Tissue Research doi: 10.1007/s00441-018-2898-7 [miExpress™ miR-451 lentiviral precursor clone]
Helsen, C.W., et al. (2018). The chimeric TAC receptor co-opts the T cell receptor yielding robust anti-tumor activity without toxicity. Nature Communications doi: 10.1038/s41467-018-05395-y [Lentifect™ Lentiviral particles expressing HER2]
Cai, M., et al. (2018). Inhibiting homologous recombination decreases extrachromosomal amplification but has no effect on intrachromosomal amplification in methotrexate‐resistant colon cancer cells. International Journal of Cancer doi: 10.1002/ijc.31781 [Lentifect™ Lentiviral particles expressing BRCA1]
Lee, J. S., et al. (2018). Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures. Cell doi: 10.1016/j.cell.2018.07.[OMICSLINK™ OTC, ORNT1 lentiviral ORF expression clones]
Wu, H., et al. (2018). Loss of neural crest‐associated gene FOXD1 impairs melanoma invasion and migration via RAC1B downregulation. International Journal of Cancer doi: 10.1002/ijc.31799 [OMICSLINK™ FOXD1 lentiviral ORF expression clone]
Liu, Z., et al. (2018). Silencing FOXC1 inhibits growth and migration of human oral squamous cell carcinoma cells. Experimental and Therepaeutic Medicine doi: 10.3892/etm.2018.6627 [OMICSLINK™ lentiviral shRNA clone set for FOX1C; Lentifect™ Lentiviral particles expressing SIP3]
Hui, K., et al. (2018). The expression and function of RASAL2 in renal cell carcinoma angiogenesis. Cell Death & Disease doi:10.1038/s41419-018-0898-x [Lentifect™ Lentiviral particles expressing RASAL2]
Guo, Y-C., et al. (2018). Ubiquitin‐specific protease USP34 controls osteogenic differentiation and bone formation by regulating BMP2 signaling. EMBO Journal doi: 10.15252/embj.201899398 [Lentifect™ Lentiviral particles expressing shRNA against USP34]
Cao, S., et al. (2018). FOXC1 induces cancer stem cell-like properties through upregulation of beta-catenin in NSCLC. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-018-0894-0 [OMICSLINK™ FOXC1 lentiviral ORF expression clone; OMICSLINK™ shRNA clone set for FOXC1]
Shigemura, M., et al. (2018). Hypercapnia increases airway smooth muscle contractility via caspase-7–mediated miR-133a–RhoA signaling. Science Translational Medicine doi: 10.1126/scitranslmed.aat1662 [miExpress™ miR-133a lentiviral precursor clone]
Hueston, C.M., et al. (2018). Chronic interleukin-1β in the dorsal hippocampus impairs behavioural pattern separation. Brain, Behavior, and Immunity doi: 10.1016/j.bbi.2018.09.015 [Lentifect™ Lentiviral particles expressing IL1β]
Franke, F.C., et al. (2018). The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial Q1 – Mesenchymal Transition and Metastasis in Colorectal Cancer. Cellular and Molecular Gastroenterology and Hepatology doi: ol Gastroenterol Hepatology doi: 10.1016/j.jcmgh.2018.08.007 [Lentifect™ Lentiviral particles expressing luciferase]
Cao, L., et al. (2018). AR–PDEF pathway promotes tumour proliferation and upregulates MYC-mediated gene transcription by promoting MAD1 degradation in ER-negative breast cancer. Molecular Cancer doi: 10.1186/s12943-018-0883-0 [Lenti-Pac™ lentiviral packaging kit; OMICSLINK™ PDEF, AR lentiviral ORF expression clones; OMICSLINK™ lentiviral shRNA clone sets for PDEF, AR]
He, Y., et al. (2018). Over-expression of IMPDH2 is associated with tumor progression and poor prognosis in hepatocellular carcinoma. American Journal of Cancer Research 2018; 8(8): 1604–1614. [Lenti-Pac™ lentiviral packaging kit]
Gangadaran, P., et al. (2018). New Optical Imaging Reporter-labeled Anaplastic Thyroid Cancer-Derived Extracellular Vesicles as a Platform for In Vivo Tumor Targeting in a Mouse Model. Scientific Reports doi: 10.1038/s41598-018-31998-y [Lentifect™ Lentiviral particles expressing RLuc]
Zhang, M., et al. (2018). Long non-coding RNA BRE-AS1 represses non-small cell lung cancer cell growth and survival via up-regulating NR4A3. Archived of Biochemistry and Biophysics doi: 10.1016/j.abb.2018.09.013 [Lentifect™ Lentiviral particles expressing STAT3]
Hing, Z.A. (2018). Targeting Nuclear Export in Chronic Lymphocytic Leukemia . Ph.D. Thesis, The Ohio State University [OMICSLINK™ BTK lentiviral ORF expression clone]
Hua, W., et al. (2018). METTL3 promotes ovarian carcinoma growth and invasion through the regulation of AXL translation and epithelial to mesenchymal transition. Gynecological Oncology doi: 0.1016/j.ygyno.2018.09.015 [OMICSLINK™ METT3L lentiviral ORF expression clone]
Liu, P., et al. (2018). PNMA1, regulated by miR-33a-5p, promotes proliferation and EMT in hepatocellular carcinoma by activating the Wnt/β-catenin pathway. Biomedicine & Pharmacotherapy doi: 10.1016/j.biopha.2018.09.059 [OMICSLINK™ lentiviral shRNA clone set for PNMA1]
Aiken, C., et al. (2018). Characterization of cellular heterogeneity in the SHH subgroup of medulloblastoma. Masters thesis, University of Manitoba [OMICSLINK™ CD271 lentiviral ORF expression clone]
Johnson, D.S., et al. (2018). SYSTEMS AND METHODS FOR MASSIVELY PARALLEL COMBINATORIAL ANALYSIS OF SINGLE CELLS. United States Patent Application 15/920,092 [Lenti-Pac™ lentiviral packaging cells]
Chiu, M., et al. (2018). Bispecific EGFR/C-Met Antibodies. United State Patent Application 15/989,532 [OMICSLINK™ HGF lentiviral ORF expression clone]
Yong, Y-X., et al. (2018). Inhibitory role of lentivirus‐mediated aquaporin‐4 gene silencing in the formation of glial scar in a rat model of traumatic brain injury. Journal of Cellular Biochemistry doi: 10.1002/jcb.27390 [OMICSLINK™ AQP4 lentiviral ORF expression clone]
Yin, B., et al. (2018). Epigenetic Control of Mesenchymal Stem Cell Fate Decision via Histone Methyltransferase Ash1l. Stem Cells doi: 10.1002/stem.2918 [OMICSLINK™ Ash1l lentiviral ORF expression clone; Lenti-Pac™ lentiviral packaging kit]
Ashraf, M. (2018). Microvesicle and stem cell compositions for therapeutic applications. United States Patent Application US20180273906A1 [Lenti-Pac™ lentiviral packaging kit]
Luo, F., eat al. (2018). Modulation of proteoglycan receptor PTPσ enhances MMP-2 activity to promote recovery from multiple sclerosis. Nature Communications doi: 10.1038/s41467-018-06505-610.1038/s41467-018-06505-6 [Lentifect™ Lentiviral particles expressing shRNA targeting MMP-2]
Kenney, R.M., et al. (2018). Paper-based Transwell assays: an inexpensive alternative to study cellular invasion. Analyst doi: 10.1039/C8AN01157E [Lentifect™ Lentiviral particles expressing shRNA targeting mCherry]
Wu, S., et al. (2018). SWI/SNF catalytic subunits’ switch drives resistance to EZH2 inhibitors in ARID1A-mutated cells. Nature Communications doi: 10.1038/s41467-018-06656-6 [OMICSLINK™ SMARCA2 lentiviral ORF expression clone]
Gupta, P., et al. (2018). HER2-mediated GLI2 stabilization promotes anoikis resistance and metastasis of breast cancer cells. Cancer Letters doi: 10.1016/j.canlet.2018.10.021 [OMICSLINK™ lentiviral shRNA clone set for GLI2]
Heidler, J., et al. (2018). Redox-proteomes of human NOS1-transduced versus MOCK SH-SY5Y neuroblastoma cells under full nutrition, serum-free starvation, and rapamycin treatment. Data in Brief doi: 10.1016/j.dib.2018.10.078 [OMICSLINK™ NOS1 lentiviral ORF expression clone]
Heidler, J., et al. (2018). Deep proteome of human nNOS/NOS1-positive versus MOCK SH-SY5Y neuroblastoma cells under full nutrition, serum free starvation and rapamycin treatment. Data in Brief doi: 10.1016/j.dib.2018.10.078 [OMICSLINK™ NOS1 lentiviral ORF expression clone]
Strassel, C., et al. (2018). Microtubule plus-end tracking Adenopolyposis Coli negatively regulates proplatelet formation. Scientific Reports doi: 10.1038/s41598-018-34118-y [OMICSLINK™ lentiviral shRNA clone set for APC]
Danhauser, K., et al. (2018). Bi-allelic ADPRHL2 Mutations Cause Neurodegeneration with Developmental Delay, Ataxia, and Axonal Neuropathy. American Journal of Human Genetics doi: 10.1016/j.ajhg.2018.10.005 [OMICSLINK™ ADPRHL2 lentiviral ORF expression clone]
Navet, B., et al. (2018). The Intrinsic and Extrinsic Implications of RANKL/RANK Signaling in Osteosarcoma: From Tumor Initiation to Lung Metastases. Cancers doi: 10.3390/cancers10110398 [OMICSLINK™ RANK, RANKL lentiviral ORF expression clones]
Lawson, J., et al. (2018). Extracellular vesicle secretion of miR‐142‐3p from lung adenocarcinoma cells induces tumor promoting changes in the stroma through cell‐cell communication. Molecular Carcinogenesis doi: 10.1002/mc.22935 [Lenti-Pac™ lentiviral packaging kit]
Shi, L., et al. (2018). MiR-148a suppressed cell invasion and migration via targeting WNT10b and modulating β-catenin signaling in cisplatin-resistant colorectal cancer cells. Biomedicine & Pharmacotherapy doi: 10.1016/j.biopha.2018.10.080 [miExpress™ miR-148a lentiviral precursor clone]
Wang, Y., et al. (2018). miR-532-3p promotes hepatocellular carcinoma progression by targeting PTPRT. Biomedicine & Pharmacotherapy doi: 10.1016/j.biopha.2018.10.145 [OMICSLINK™ PTPRT lentiviral ORF expression clone; OMICSLINK™ lentiviral shRNA clones set for PTPRT]
Hua, Y., et al. (2018). Dual androgen receptor (AR) and STAT3 inhibition by a compound targeting the AR amino ‐ terminal domain. Pharmacologocal Research Perspectives doi: 10.1002/prp2.437 [OMICSLINK™ lentiviral ORF expression clone]
Wang, C., et al. (2018). Transcriptomic Analysis of Histone Methyltransferase Setd7 Knockdown and Phenethyl Isothiocyanate in Human Prostate Cancer Cells. Anticancer Research doi: 10.21873/anticanres.12957 [OMICSLINK™ lentiviral shRNA clone set for SETD7]
Qin, H., et al. (2018). Preclinical Development of Bivalent Chimeric Antige n Receptors Targeting Both CD19 and CD22. Molecular Therapy: Oncolytics doi: 10.1016/j.omto.2018.10.006 [OMICSLINK™ CD22 lentiviral ORF expression clone]
Xi, L-C., et al. (2018). Long non-coding RNA-2271 promotes osteogenic differentiation in human bone marrow stem cells. Open Life Sciences doi: 10.1515/biol-2018-0049 [Lenti-Pac™ lentiviral packaging kit]
Jackson, T.C., et al. (2018). Infants Uniquely Express High Levels of RBM3 and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain. Developmental Neuroscience doi: 10.1159/000493637 [Lenti-Pac™ lentiviral packaging cells]
Roush, W.R., et al. (2018). THERAPEUTIC TARGETING OF CASEIN KINASE 1 DELTA IN BREAST CANCER. United States Patent Application 15/768,257 [OMICSLINK™ CK18 lentiviral ORF expression clone]
Durán, J.G.B., et a. (2018). In vitro conversion of adult murine endothelial cells to hematopoietic stem cells. Nature Protocols doi: 10.1038/s41596-018-0060-3 [OMICSLINK™ FosB, Gfi1, Runx1, Spi1 lentiviral ORF expression clones]
Delcroix, V., et al. (2018). The Role of the Anti-Aging Protein Klotho in IGF-1 Signaling and Reticular Calcium Leak: Impact on the Chemosensitivity of Dedifferentiated Liposarcomas. Cancers doi: 10.3390/cancers10110439 [OMICSLINK™ KL lentiviral ORF expression clone]
Marques, M., et al. (2018). Oncogenic activity of poly (ADP-ribose) glycohydrolase. Oncogene doi: 10.1038/s41388-018-0568-6 [OMICSLINK™ PARG lentiviral ORF expression clones]
Yang, G., et al. (2017). MicroRNA-195 protection against focal cerebral ischemia by targeting CX3CR1. Journal of Neurosurgery doi: 10.3171/2018.5.JNS173061 [Lentifect™ Lentiviral particles]
Xie, X-W., et al,. (2018). Effect of Upregulated DNA Replication and Sister Chromatid Cohesion 1 Expression on Proliferation and Prognosis in Hepatocellular Carcinoma. Chinse Medical Journal doi: 10.4103/0366-6999.246076 [OMICSLINK™ lentiviral shRNA clone set for DCC1]
Yeung, T-L., et al. (2018). ISG15 Promotes ERK1 ISGylation, CD8+ T Cell Activation and Suppresses Ovarian Cancer Progression. Cancers doi: 10.3390/cancers10120464 [Lentifect™ Lentiviral particles expressing ISG15 ORF]
Kozareva, D.A., et al. (2018). TLX knockdown in the dorsal dentate gyrus of juvenile rats differentially affects adolescent and adult behaviour. Behavioural Brain Research doi: 10.1016/j.bbr.2018.11.034 [Lentifect™ Lentiviral particles expressing shRNA]
Chen, Y., et al. (2018). LncRNA MALAT1 Promotes Cancer Metastasis in Osteosarcoma via Activation of the PI3K-Akt Signaling Pathway. Cellular Physiology and Biochemistry doi: 10.1159/000495550 [OMICSLINK™ MALAT2 lentiviral expression clone]
Gao, J., et al. (2018). Intratumoral radiofrequency hyperthermia-enhanced chemotherapy of liposomal doxorubicin on hepatocellular carcinoma. Am J Transl Res 2018;10(11):3619-3627 [OMICSLINK™ luciferase, mCherry lentiviral ORF expression clones]
Liu, Z., et al. (2018). Muscular proteomic profiling of deep pressure ulcers reveals myoprotective role of JAK2 in ischemia and reperfusion injury. Am J Transl Res 2018;10(11):3413-3429 [Lentifect™ Lentiviral particles expressing JAK2 ORF]
Wang, M., et al. (2018). Zerumbone inhibits migration in ESCC via promoting Rac1 ubiquitination. Biomedicine & Pharmacotherpay doi: 10.1016/j.biopha.2018.11.134 [Lenti-Pac™ lentiviral packaging kit]
He, R., et al. (2018). miR‐146b overexpression ameliorates lipopolysaccharide‐induced acute lung injury in vivo and in vitro. Journal of Cellular Biochemistry doi: 10.1002/jcb.26846 [Lenti-Pac™ lentiviral concentration solution]
Wang, S., et al. (2018). SUR2B/Kir6.1 channel openers correct endothelial dysfunction in chronic heart failure via the miR-1-3p/ET-1 pathway. Biomedicine & Pharmacotherapy doi: 10.1016/j.biopha.2018.11.135 [Lenti-Pac™ lentiviral packaging cells]
Gao, L.R., et al. (2018). Overexpression of apelin in Wharton’ jelly mesenchymal stem cell reverses insulin resistance and promotes pancreatic β cell proliferation in type 2 diabetic rats. Stem Cell Research & Therapy doi: 10.1186/s13287-018-1084-x [OMICSLINK™ GV208-apelein lentiviral ORF expression clone]
Cianfarani, F., et al. (2018). Decorin counteracts disease progression in mice with recessive dystrophic epidermolysis bullosa. Matrix Biology doi: 10.1016/j.matbio.2018.12.001 [OMICSLINK™ Decorin lentiviral ORF expression clone]
Miura, N., et al. (2018). Inhibitors for methylation-related enzymes hat1 and kat8. United Stated Patent Application 15/771,958 [Lentifect™ Lentiviral particles expressing shRNA targeting HAT1, KAT8]
Harirchian, P., et al. (2018). A20 and ABIN1 suppression of a keratinocyte inflammatory program with a shared single cell expression signature in diverse human rashes. Journal of Investigative Dermatology doi: 10.1016/j.jid.2018.10.046 [OMICSLINK™ ABIN, A20 lentiviral ORF expression clones]
Xue, Y., et al. (2018). IL-17A modulates osteoclast precursors' apoptosis through autophagy-TRAF3 signaling during osteoclastogenesis. Biochemical and Biophysical Research Communications doi: 10.1016/j.bbrc.2018.12.029 [Lentifect™ Lentiviral particles expressing Beclin]
Lu, Y., et al. (2018). DNA demethylation facilitates the specific transcription of the mouse X-linked Tsga8 gene in round spermatids. Biology of Reproduction doi: 10.1093/biolre/ioy255 [GLuc-ON™ Tsga8 lentiviral promoter-reporter clone]
Cheng, F., et al. (2018). Conversion of human adipose-derived stem cells into functional and expandable endothelial-like cells for cell-based therapies. Stem CEll Research and Therapy doi: 10.1186/s13287-018-1088-6 [Lentiviral particles expressing sgRNA targeting MVPEGM-2]
Offenhäuser, C., et al. (2018). EphA3 Pay-Loaded Antibody Therapeutics for the Treatment of Glioblastoma. Cancers doi: 10.3390/cancers10120519 [Lentifect™ Lentiviral particles expressing luciferase]
Wang, J., et al. (2018). Fibrinogen-like Protein 1 Is a Major Immune Inhibitory Ligand of LAG-3. Cell doi: 10.1016/j.cell.2018.11.01074 [Lenti-Pac™ lentiviral packaging kit]
Li, S., et al. (2018). IL-17A inhibits autophagic activity of HCC cells by inhibiting the degradation of Bcl2. Biochemical and Biophysical Research Communications doi: 10.1016/j.bbrc.2018.12.103 [Lentifect™ Lentiviral particles expressing Beclin]
Li, J., et al. (2018). HIF1A and VEGF regulate each other by competing endogenous RNA mechanism and involve in the pathogenesis of peritoneal fibrosis. Pathology- Research & Practice doi: 10.1016/j.prp.2018.12.022 [Lentifect™ Lentiviral particles for overexpression and shRNA of HIF1A, VEGF]
Rahman, A.A. (2018). INVESTIGATING AUTOPHAGY DYSFUNCTION INDUCED BY A PARKINSON’S DISEASE – CAUSING MUTATION IN VPS35. Ph.D. Thesis, Boise State University [Lenti-Pac™ lentiviral packaging cells]
Zhou, X-L., et al. (2019). The oncoprotein HBXIP competitively binds KEAP1 to activate NRF2 and enhance breast cancer cell growth and metastasis. Oncogene doi: 10.1038/s41388-019-0698-5 [Lentifect™ Lentiviral particles expressing CRE]
Huang, C., et al. (2019). Antigen Binding Regions Against Fibronectin Type III Domains and Methods of Using The Same. United States Patent Application 16/037,340, 2019 [OMICSLINK™ FCRGs lentiviral ORF expression clones]
Firas, J., et al. (2019). Cell reprogramming. United States Patent Application 16/064,905 [OMICSLINK™ lentiviral ORF expression clones]
Zhou, X., et al. (2019). Metformin Inhibit Lung Cancer Cell Growth and Invasion in Vitro as Well as Tumor Formation in Vivo Partially by Activating PP2A. Medical Science Monitor doi: 10.12659/MSM.912059 [OMICSLINK™ lentiviral shRNA clone sets]
Sukonina,, V., et al. (2019). FOXK1 and FOXK2 regulate aerobic glycolysis. Nature doi: 10.1038/s41586-019-0900-5 [Lentifect™ Lentiviral particles expressing FOXK1, FOXK2]
Nagaraj, A.B., et al. (2019). A miRNA-Mediated Approach to Dissect the Complexity of Tumor-Initiating Cell Function and Identify miRNA-Targeting Drugs. Sem Cell Reports doi: 10.1016/j.stemcr.2018.12.002 [miArrest™ miR-181 lentiviral inhibitor clone]
Xiong, X., et al. (2019). LINC00052 functions as a tumor suppressor through negatively modulating miR‐330‐3p in pancreatic cancer. Journal of Cellular Physiology doi: 10.1002/jcp.28209 [Lenti-Pac™ lentiviral packaging kit]
Fitchman, B., et al. (2019). Combined loss of LAP1B and LAP1C results in an early onset multisystemic nuclear envelopathy. Nature Comunications doi: 10.1038/s41467-019-08493-7 [Lentifect™ Lentiviral particles expressing LAP1B, LAP1C]
Liu, Y-N., et al. (2019). Sphingosine 1 phosphate receptor-1 (S1P1) promotes tumor-associated regulatory T cell expansion: leading to poor survival in bladder cancer. Cell Death & Disease doi: 10.1038/s41419-018-1298-y [OMICSLINK™ SIP1 lenticiral shRNA clone set]
Xie, X., et al. (2019). MiR -192- 5p reverses cisplatin resistance by targeting ERCC3 and ERCC4 in SGC7901/DDP cells. Journal of Cancer doi:10.7150/ jca .25814 [Lentifect™ Lentiviral particles expressingmiR-192-5p]
Xue, Y., et al. (2019). SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer. Nature Communications doi: 10.1038/s41467-019-08380-1 [OMICSLINK™ SMARCA2, SMARCA4 lentiviral ORF expression clones]
Xue, Y., et al. (2019). CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary. Nature Communications doi: 10.1038/s41467-018-06958-9 [OMICSLINK™ SMARCA4 lentiviral ORF expression clone]
Barnawi, R., et al. (2019). β1 Integrin is Essential for Fascin‐Mediated Breast Cancer Stem Cell Function and Disease Progression. International Journal of Cancer doi: 10.1002/ijc.32183 [Lentifect™ Lentiviral particles expressing fascin]

>2017

Xing, F., et al. (2017). The Anti-Warburg Effect Elicited by the cAMP-PGC1α Pathway Drives Differentiation of Glioblastoma Cells into Astrocytes. Cell Reports doi: 10.1016/j.celrep.2016.12.037 [Lenti-Pac™ lentiviral packaging kit]
Teng, Y., et al. (2017). MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression. Nature Communications doi: 10.1038/ncomms14448 [Lentiviral particles expressing sgRNA targeting MVP]
Jay, A. (2017). STUDIES OF CD36 INTERACTING WITH FATTY ACIDS, OXIDIZED LOW DENSITY LIPOPROTEIN, AND THE CELLULAR PLASMA MEMBRANE. Thesis Dissertation, Boston University [CD36 ORF lentiviral particles]
Liu, Y., et al. (2017). Latexin Inactivation Enhances Survival and Long-Term Engraftment of Hematopoietic Stem Cells and Expands the Entire Hematopoietic System in Mice. Stem Cell Reports doi: 10.1016/j.stemcr.2017.02.009 [Lentifect™ lentviral particles]
Shih Y.P., et al. (2017). Down-regulation of DLC1 in endothelial cells compromises the angiogenesis process. 10.1016/j.canlet.2017.04.004 [lentivirus expressing SV40 large T antigen]
Wu, M., et al. (2017). Immunomodulators Targeting MARCO Expression Improve Resistance to Post-influenza Bacterial Pneumonia. Lung Cellular and Molecular Physiology doi: 10.1152/ajplung.00075.2017 [lentivirus expressing TFEB ORF]
Qi, W., et al. (2017). Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction. Nature Medicine doi: 10.1038/nm.4328 [Lentifect™ Human PKM1 and PKM2 lentivirus]
Burenkova, O., et al. (2017). BIOMARKERS FOR PREDICTING OUTCOMES OF CANCER THERAPY WITH ERBB3 INHIBITORS. United States Patent Application 20170101480 [Lentifect™ ErbB4 JMaCYT1 and ErbB4 JMaCYT2 isoform cDNA lentivirus]
Liu, L., et al. (2017). CRY2 is suppressed by FOXM1 mediated promoter hypermethylation in breast cancer. Biochemical and Biophysical Research Communications doi: 10.1016/j.bbrc.2017.06.003 [FOXM1 Human Lentifect™ Purified Lentiviral Particles]
Chen, X., et al. (2017). MicroRNA-195 prevents dendritic degeneration and neuron death in rats following chronic brain hypoperfusion. Cell Death & Disease doi: 10.1038/cddis.2017.243 [Lentifect™ lentiviral particles expressing miR-195 miRNA precursors]
Tian, F.M., et al. (2017). PDE3A is hypermethylated in cisplatn resistant non-small cell lung cancer cells and is a modulator of chemotherapy response. European Review for Medical and Pharmacological Sciences 2017; 21: 2635-2641 [Lentifect™ lentiviral particles expressing PDE3A]
Yang, G., et al. (2017). CD11b promotes the differentiation of osteoclasts induced by RANKL through the spleen tyrosine kinase signalling pathway. Jounral of Cellular and Molecular Medicine doi: 10.1111/jcmm.13254 [Lentifect™ lentiviral particles expressing Itgam shRNA (shCD11b-1, shCD11b-2)]
Kalimuthu, S., et al. (2017). In Vivo Tracking of Chemokine Receptor CXCR4-Engineered Mesenchymal Stem Cell Migration by Optical Molecular Imaging. Stem Cells International doi: /10.1155/2017/8085637 4 [Lentifect™ lentiviral particles expressing mCherry-RLuc]
dos Santos, A.L., et al. (2017). Acid-sensitive lipidated doxo…prodrug entrapped in nanoemulsion impairs lung tumor metastasis in a breast cancer model. Furure Medicine doi: 10.2217/nnm-2017-0091 [Lentifect™ lentiviral particles expressing Firefly luciferase]
Han, M., et al. (2017). EMP3 is induced by TWIST1/2 and regulates epithelial-to-mesenchymal transition of gastric cancer cells. Tumor Biology doi: 10.1177/1010428317718404 [TWIST1 and TWIST2 Lentifect™ purified lentiviral particles]
Mondal, G., et al. (2017). EGFR-Targeted Cationic Polymeric Mixed Micelles for Codelivery of Gemcitab…and miR-205 for Treating Advanced Pancreatic Cancer. Molecular Pharmaceutics doi: 10.1021/acs.molpharmaceut.7b00355 [Lentiviral particles expressing luciferase]
Wu, D., et al. (2017). SLC39A4 expression is associated with enhanced cell migration, cisplatn resistance, and poor survival in non-small cell lung cancer. Scientific Reports doi: 10.1038/s41598-017-07830-4 [Lentifect™ purified lentiviral particles]
Li, Y., et al. (2017). Targeted Disruption of TCF12 Reveals HEB as Essential in Human Mesodermal Specification and Hematopoiesis. Stem Cell Reports doi: 10.1016/j.stemcr.2017.07.011 [Lentifect™ purified lentiviral particles expressing HEBCan]
Man, L., et al. (2017). Engineered endothelium provides angiogenic and paracrine stimulus to grafted human ovarian tissue. Scientific Reports doi: 10.1038/s41598-017-08491-z [Lentifect™ purified lentiviral particles]
Wang, W., et al. (2017). P2Y6 Regulates cytoskeleton reorganization and cell migration of C2C12 myoblasts via ROCK pathway. Journal of Cellular Biochemistry doi: 10.1002/jcb.26350 [Lentifect™ purified lentiviral particles expressing P2Y6]
Kim, K.M., et al. (2017). Identification of senescent cell surface targetable protein DPP4. Genes & Development doi: 10.1101/gad.302570.117 [Lentifect™ purified lentiviral particles expressing DPP-4]

2016

Emery, AC. et al. (2016) C-terminal amidation of PACAP-38 and PACAP-27 is dispensable for biological activity at the PAC1 receptor. Peptides,doi:10.1016/j.peptides.2016.03.003. [human PAC1hop receptor with a C-terminal V5 epitope tag was encoded in the pLx304 lentiviral vector]
Huang, Z. et al. (2016) Cdc42 deficiency induces podocyte apoptosis by inhibiting the Nwasp/stress fibers/YAP pathway. Cell Death & Disease,Cell Death and Disease (2016) 7, e2142; doi:10.1038/cddis.2016.51. [Lentiviral packaging wild-type YAP or YAP S112A mutation plasmids (CS-Mm06093-Lv128)]
Hoang, B. et al. (2016) SGK kinase activity in multiple myeloma cells protects against ER stress apoptosis via a SEK-dependent mechanism.. Molecular Cancer Research, doi:10.1158/1541-7786.MCR-15-0422. [pReceiver SEK1(EX-A0727-Lv105), pReceiver-Lv105 (EX-NEG-Lv105)]
Jiang, Z. et al. (2016) The effects and mechanisms of SLC34A2 on tumorigenicity in human non-small cell lung cancer stem cells. Tumor Biology,doi:10.1007/s13277-016-4928-y. [NC-si-RNA, SLC34A2-si-RNA lentiviral knock- downs, or Bmi1-si-RNA lentiviral knockdowns]
Pan, X. et al. (2016) Quinalizarin enhances radiosensitivity of nasopharyngeal carcinoma cells partially by suppressing SHP-1 expression. International Journal of Oncology,Pages: 1073-1084 DOI: 10.3892/ijo.2016.3338. [lentivirus-mediated SHP-1 overexpression]
Choi, YJ. et al. (2016) Visualization of the Biological Behavior of Tumor-Associated Macrophages in Living Mice with Colon Cancer Using Multimodal Optical Reporter Gene Imaging. Neoplasia,doi:10.1016/j.neo.2016.01.004. [lentivirus coexpressing the Rluc and mCherry genes]
Carter , SL. et al. (2016) IκBα mediates prostate cancer cell death induced by combinatorial targeting of the androgen receptor. BMC Cancer,DOI: 10.1186/s12885-016-2188-2. [NFKBIA-IRES-eGFP lentiviral ORF plasmid]
You, A. et al. (2016) Metformn sensitizes sorafenb to inhibit postoperative recurrence and metastasis of hepatocellular carcinoma in orthotopic mouse models. Journal of Hematology & Oncology,DOI: 10.1186/s13045-016-0253-6. [EX-M0910-Lv105-5, overexpress control (EX-eGFP-Lv-105), and Lenti-Pac™HIV Expression Packaging Kit (Cat. No. HPK-LvTR-20)]
Eno, MR. et al. (2016) P450 3A Catalyzed O-dealkylation of Lapatinib Induces Mitochondrial Stress and Activates Nrf2. Chemical Research in Toxicology,DOI: 10.1021/acs.chemrestox.5b00524. [Lentiviruses, lentiviral plasmids, and reagents]
Jiang, P. et al. (2016) Proaggregant nuclear factor (s) trigger rapid formation of α-synuclein aggregates in apoptotic neurons. Acta Neuropathologica,DOI: 10.1007/s00401-016-1542-4. [Lentiviral plasmids and virus preparation Lentiviral plasmids carrying Αs (EX-G0543-Lv105)]
Layek , B. et al. (2016) Glycoengineered Mesenchymal Stem Cells as an Enabling Platform for Two-Step Targeting of Solid Tumors. Biomaterials,doi:10.1016/j.biomaterials.2016.02.024. [Firefly Luciferase Lentifect™ Purified Lentiviral Particles]
Wilkinson, D.C., et al. (2016). Development of a Three-Dimensional Bioengineering Technology to Generate Lung Tissue for Personalized Disease Modeling Stem Cells Translational Medicine doi: 10.5966/sctm.2016-0192 [ACTA2-mCherry lentiviral particles]
González-Mariscal, I., et al. (2016). Human CB1 Receptor Isoforms, present in Hepatocytes and β-cells, are Involved in Regulating Metabolism. Scientific Reports doi: 10.1038/srep33302 [Lentifect™ Lentiviral particles]
Kalimuthu, S., et al. (2016). In Vivo therapeutic potential of mesenchymal stem cell-derived extracellular vesicles with optical imaging reporter in tumor mice model. Scientific Reports doi: 10.1038/srep30418 [Renilla luciferase-expressing lentiviral particles]
Vishnubalaji, R., et al. (2016). Bone morphogenetic protein 2 (BMP2) induces growth suppression and enhances chemosensitivity of human colon cancer cells. Cancer Cell International doi: 10.1186/s12935-016-0355-9 [human BMP2 and GFP control lentiviral particles]
Barnawi, R., et al. (2016). Fascin is Critical for the Maintenance of Breast Cancer Stem Cell Pool Predominantly via the Activation of the Notch Self-Renewal Pathway. Stem Cells doi: 10.1002/stem.2473 [Lentifect™ Fascin ORF-expressing lentiviral particles]
Ilmer, M., et al. (2016). Cell surface galectin-3 defines a subset of chemoresistant gastrointestinal tumor-initiating cancer cells with heightened stem cell characteristics. Cell Death & Disease doi: 10.1038/cddis.2016.239 [Lentifect™ mCherry-expressing lentiviral particles]
Lai, Y., et al. (2016). MiR-384 regulated IRS1 expression and suppressed cell proliferation of human hepatocellular carcinoma. Tumor Biology doi: 10.1007/s13277-016-5233-5 [Lentifect™ lentiviral particles expressing shRNA targeting IRS1]
Zhang, H., et al. (2016). CXCL2/MIF-CXCR2 signaling promotes the recruitment of myeloid-derived suppressor cells and is correlated with prognosis in bladder cancer. Oncogene doi: 10.1038/onc.2016.367 [Lentifect™ lentiviral particles expressing MyD88]
Voloshin, T., et al. (2016). Alternating electric fields (TTFields) in combination with paclitaxl are therapeutically effective against ovarian cancer cells in vitro and in vivo. International Journal of Cancer doi: 10.1002/ijc.30406 [Lentifect™ firefly luciferase-expressing lentiviral particles]
Zhu, S., et al. (2016). Helicobacter pylori-induced cell death is counteracted by NF-κB-mediated transcription of DARPP-32 . Gut doi: 10.1136/gutjnl-2016-312141 [DARPP-32 shRNA lentiviral particles]
Ghosh, S., et al. (2016). Targeted proteomics of cannabinoid receptor CB1 and the CB1b isoform. Journal of Pharmaceutical and Biomedical Analysis doi: 10.1016/j.jpba.2016.11.003 [Lentifect™ lentviral particles]
Wu, J., et al. (2016). Umbilical cord blood-derived non-hematopoietic stem cells retrieved and expanded on bone marrow-derived extracellular matrix display pluripotent characteristics. Stem Cell Research and Theraoy doi: 10.1186/s13287-016-0437-6 [Lentifect™ lentviral particles expressing eGFP]

2015

Ginsberg, M. et al. (2015) Direct conversion of human amniotic cells into endothelial cells without transitioning through a pluripotent state. Nature Protocols,doi:10.1038/nprot.2015.126. [clone cDNAs encoding ETV2, ERG1 and FLI1 into the lentiviral backbone pCCL-PGK lentivirus vector]
Ahlenstiel, C. et al. (2015) Novel RNA duplex locks HIV-1 in a latent state via chromatin-mediated transcriptional silencing. Molecular Therapy Nucleic Acids,doi:10.1038/mtna.2015.31. [lentiviral vectors containing the reporter mCherry]
Zhao, Z. et al. (2015) RNA interference targeting PSCA suppresses primary tumor growth and metastasis formation of human prostate cancer xenografts in SCID mice. The Prostate,DOI: 10.1002/pros.23110. [lentiviral vector pEZ-Lv201]
Mazzone, M. et al. (2015) MODULATING TRANSENDOTHELIAL MIGRATION AND RECRUITMENT OF GRANULOCYTES BY MODULATING C-MET PATHWAY. US Patent ,US Patent 20,150,258,194, 2015. [luciferase-expressing lentivirus (EXhLUC-Lvl 14)]
Lisanti, MP. et al. (2015) MSF REPROGRAMS MYOFIBROBLASTS TOWARD LACTATE PRODUCTION AND FUEL ANAERBOIC TUMOR GROWTH. US Patent,US Patent 20,150,240,240. [[EX-NEG-Lv105 (empty vector), Ex- Z4998-Lv105 (human MSF),Ex-D0101-Lv105 (human SMA), Ex-A0247-Lv105 (human Rac1), Ex-X0047-Lv105 (human Cdc42)]
Zavattari, P. et al. (2015) Nrf2, but not β‐catenin, mutation represents an early event in rat hepatocarcinogenesis. Hepatology,DOI: 10.1002/hep.27790. [a NRF2 lentiviral construct (217EX- T3128-Lv157), KEAP1 encoding plasmid (pCDNA3- T7-Keap1)]
Chen, H. et al. (2015) Requirement for BUB1B/BUBR1 in tumor progression of lung adenocarcinoma. Genes & Cancer,Genes & Cancer, Vol. 6 (3-4), March 2015. [pReceiver-Lv141 lentiviral vector]
Mcmillan, M. et al. (2015) CELL THERAPY TECHNOLOGY TO DELIVER RADIO-PROTECTIVE PEPTIDES. US Patent ,US Patent 20,150,050,250. [pLV67 lentiviral vector]
Liu, X. et al. (2015) The Regulation and Function of miR-21-FOXO3a-miR-34b/c Signaling in Breast Cancer. International Journal of Molecular Sciences ,Int. J. Mol. Sci. 2015, 16, 3148-3162; doi:10.3390/ijms16023148. [Lentiviral plasmids expressing FOXO3a and PTEN]
Xu, Y. et al. (2015) Expression and functional role of miR-29b in renal cell carcinoma. International Journal of Clinical and Experimental Pathology,Int J Clin Exp Pathol. 2015; 8(11): 14161–14170.. [hsa-miR-29b lentivirus expression vector ]
Yuste‐Checa , P. et al. (2015) The Effects of PMM2‐CDG‐Causing Mutations on the Folding, Activity, and Stability of the PMM2 Protein. Human Mutation,doi: 10.1002/humu.22817. [human PMM2 lentiviral ORF (EX-M0134-Lv101)]
Wang , Z. et al. (2015) Syndecan-1 Acts in Synergy with Tight Junction Through Stat3 Signaling to Maintain Intestinal Mucosal Barrier and Prevent Bacterial Translocation.. Inflammatory Bowel Diseases,doi: 10.1097/MIB.0000000000000421. [lentiviral plasmid containing human Sdc1, constitu- tively active Stat3 (Stat3 C), or dominant-negative Stat3 (Stat3 DN)]
Barrault , C. et al. (2015) Androgens induce sebaceous differentiation in sebocyte cells expressing a stable functional androgen receptor. The Journal of Steroid Biochemistry and Molecular Biology,doi:10.1016/j.jsbmb.2015.04.005. [full length AR gene-expressing lentiviral vectors previously constructed with the expression plasmid vector EX-E2325]
Vitali , C. et al. (2015) SOCS2 controls proliferation and stemness of hematopoietic cells under stress conditions and its deregulation marks unfavourable acute leukemias.. Cancer Research,Published OnlineFirst April 9, 2015; doi: 10.1158/0008-5472.CAN-14-3625. [mouse Mef2c (NMB001170537) lentviral ORF and Ikzf1(NMB001025597) or the empty vector]
Allahverdi, A. et al. (2015) Lentiviral vectors titration using real-time PCR. Journal of Paramedical Sciences,. [Lentiviral vector EX-M0942-Lv105 plasmid]
PAN, XF. et al. (2015) SHP-1 overexpression increases the radioresistance of NPC cells by enhancing DSB repair, increasing S phase arrest and decreasing cell apoptosis. Oncology Reports,Pages: 2999-3005 DOI: 10.3892/or.2015.3939. [SHP-1 gene sequence and a negative oligo sequence were inserted into pEZ-Lv201-green fluorescent protein (gFP) lentiviral vectors]
Zhangi , P. et al. (2015) ILT4 drives B7-H3 expression via PI3K/AKT/mTOR signalling and ILT4/B7-H3 co-expression correlates with poor prognosis in non-small cell lung cancer. FEBS Letters,DOI: 10.1016/j.febslet.2015.06.037. [Pez-lv105-ILT4 (ILT4), and a negative control plasmid, Pez-lv105 (NC)]
Wu , W. et al. (2015) miR-30c negatively regulates the migration and invasion by targeting the immediate early response protein 2 in SMMC-7721 and HepG2 cells. American Journal of Cancer Research,Am J Cancer Res. 2015; 5(4): 1435–1446.. [The vectors expressing IER2 (pEZ- Lv105-IER2) and null (pEZ-Lv105-null)]
Takeuchi , A. et al. (2015) STAT5A regulates DNMT3A in CD34+/CD38− AML cells. Leukemia Research,doi:10.1016/j.leukres.2015.05.006. [control and STAT5A lentiviral vectors]
Yuan, H. et al. (2015) MicroRNA-1908 is upregulated in human osteosarcoma and regulates cell proliferation and migration by repressing PTEN expression. Oncology Reports,Oncol Rep. 2015 Nov;34(5):2706-14. doi: 10.3892/or.2015.4242. Epub 2015 Sep 1. [lentiviral plasmid pEZX- MR03 expressing 1908 (Cat,HmiR0274-MR03) or scrambled miRNA (Cat, CmiR0001-MR03) and Lenti-Pac HIV Expression Packaging mix]
Xie, H. et al. (2015) Nuclear EGFRvIII Resists Hypoxic Microenvironment Induced Apoptosis via Recruiting ERK1/2 Nuclear Translocation. Biochemical and Biophysical Research Communications,Volume 470, Issue 2, 5 February 2016, Pages 466–472. [EGFRvIII/EGFRvIIIdNLS in pReceiver-LV151, Lenti-Pac HIV Expression Packaging Kit]
Cao, M. et al. (2015) HIF-2α regulates CDCP1 to promote PKCδ-mediated migration in hepatocellular carcinoma. Tumor Biology,DOI
10.1007/s13277-015-3527-7. [lentiviral plasmid HIF-2α (Cat.No.EX-M0910-Lv105-5), overexpression control (Cat.No.EX-eGFP-Lv-105), and Lenti-Pac™ HIV Expression Packaging Kit (Cat.No. HPK-LvTR-20)]
Okada, M. et al. (2015) Abrogation of Age‐Induced Microrna‐195 Rejuvenates the Senescent Mesenchymal Stem Cells by Reactivating Telomerase. STEM CELLS,DOI: 10.1002/stem.2211. [Lenti-Pac HIV Expression Packaging System]
Rodriguez, AL. et al. (2015) Tailoring minimalist self-assembling peptides for localised viral vector gene delivery. Nano Research,March 2016, Volume 9, Issue 3, pp 674-684. [mCherry lentivirus]
Lin, T. et al. (2015) MicroRNA-378g enhanced radiosensitivity of NPC cells partially by targeting protein tyrosine phosphatase SHP-1. International Journal of Radiation Biology,DOI:10.3109/09553002.2015.1096028. [Lentiviruses containing the SHP-1 gene (LP-SHP-1) and negative oligomers (LP-Neg)]
Qadir, XV. et al (2015) miR-223 Deficiency Protects against Fas-Induced Hepatocyte Apoptosis and Liver Injury through Targeting Insuln-Like Growth Factor 1 Receptor. American Journal of Pathology,185(12):3141-3151. [lentiviral particle solution containing either scrambled control miRNA (L/control) or pre–miR-223 (L/miR-223)]
Hoffman, Jill M. et al. (2015) Corticotropin-Releasing Hormone Receptor 2 Signaling Promotes Mucosal Repair Responses after Colitis. The American Journal of PATHOLOGY,January 2016Volume 186, Issue 1, Pages 134–144. [MCS-IRES-Strawberry-hPGK-Puro lentiviral particles that contained a cytomegalovirus promoter driving expression of human CRHR2]
Kenney, RM. et al. (2015) Real-time imaging of cancer cell chemotaxis in paper-based scaffolds. Analyst,DOI: 10.1039/c5an01787d . [lentiviral particles (LPP-eGFP-Lv105-025)]
Truong, AS. et al. (2015) Tracking the invasion of small numbers of cells in paper-based assays with quantitative PCR. Analytical Chemistry,DOI: 10.1021/acs.analchem.5b02362. [lentiviral particles, LPP-EGFP-Lv105-025 and LPP-MCHR-Lv105-025 particles, Lenti-Pac HIV Expression Packaging Kit]
Zhu, S. et al. (2015) Regulation of CD44E by DARPP-32-dependent activation of SRp20 splicing factor in gastric tumorigenesis. Oncogene,Oncogene 35, 1847-1856 (07 April 2016) | doi:10.1038/onc.2015.250. [Lentivirus particles expressing DARPP-32 shRNA or control shRNA]
Samarakoon, R. et al. (2015) Loss of Tumour Suppressor PTEN Expression in Renal Injury Initiates SMAD3 and p53 Dependent Fibrotic Responses. The Journal of Pathology,DOI: 10.1002/path.4538. [PTEN human ORF cDNA or control Lentifect lentiviral particles]
Becker , S. et al. (2015) Allogeneic Transplantation of Müller-Derived Retinal Ganglion Cells Improves Retinal Function in a Feline Model of Ganglion Cell Depletion. Stem Cells Translational Medicine,http://dx.doi.org/
10.5966/sctm.2015-0125. [eGFP lentiviral particles]
Mondal , G. et al. (2015) EGFR Targeted Polymeric Mixed Micelles carrying Gemcitabne for treating Pancreatic Cancer. Biomacromolecules,DOI: 10.1021/acs.biomac.5b01419. [Lentiviral particle LP-hLUC-Lv201- 0200]
Brown , AR. et al. (2015) Krüppel-like Factor 9 (KLF9) prevents colorectal cancer through inhibition of interferon-related signaling. Carcinogenesis,Carcinogenesis (2015)
doi: 10.1093/carcin/bgv104. [lentiviral particles containing cDNA for green fluorescent protein (EGFP) or human KLF9]
Boyce, MW. et al. (2015) Quantifying oxygen in paper-based cell cultures with luminescent thin film sensors. Analytical and Bioanalytical Chemistry,DOI
10.1007/s00216-015-9189-x. [lentiviral particles (LPP-eGFP-Lv105-025)]
Truong, AS. et al. (2015) Tracking the invasion of small numbers of cells in paper-based assays with quantitative PCR. Analytical Chemistry,DOI: 10.1021/acs.analchem.5b02362. [lentiviral particles, LPP-EGFP-Lv105-025 and LPP-MCHR-Lv105-025 particles, Lenti-Pac HIV Expression Packaging Kit]
Chen, W. et al. (2015) Deletion of Mir155 Prevents Fas-Induced Liver Injury through Up-Regulation of Mcl-1. The American Journal of Pathology,Volume 185, Issue 4, April 2015, Pages 1033–1044. [pre-Mir155 lentivirus and scrambled control miRNA]

2014

Lee, R. et al. (2014) Regulated Inositol‐Requiring Protein 1‐Dependent Decay as a Mechanism of Corin RNA and Protein Deficiency in Advanced Human Systolic Heart Failure. Journal of the American Heart Association,doi: 10.1161/JAHA.114.001104. [mouse IRE1 Lentiviral ORF]
Gan, M. et al. (2014) Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Regulates the Stability and Function of GluA1 α-Amino-3-Hydroxy-5-Methyl-4-Isoxazole Propionic A. PLOS ONE,Published: December 12, 2014http://dx.doi.org/10.1371/journal.pone.0113237. [Lentiviral plasmid CS-Mm02851-Lv206 for expression of GluA1]
Wang, Y. et al. (2014) Ephrin type‑A receptor 2 regulates sensitivity to paclitaxl in nasopharyngeal carcinoma via the phosphoinositide 3‑kinase/Akt signalling pathway. Molecular medicine reports,Pages: 924-930 DOI: 10.3892/mmr.2014.2799. [EphA2‑specific cDNA lentiviral plasmids (EX‑A0125‑Lv105)]
Anchan, RM. et al. (2014) Pax6-and Six3-Mediated Induction of Lens Cell Fate in Mouse and Human ES Cells. PLOS ONE,Published: December 17, 2014http://dx.doi.org/10.1371/journal.pone.0115106. [EX-Mm04345-Lv33 lentiviral vector]
Bill, A. et al. (2014) Variomics screen identifies the reentrant loop of the calcium-activated chloride channel ANO1 that facilitates channel activation. Journal of Biological Chemistry,First Published on
November 25, 2014
doi: 10.1074/jbc.M114.618140. [pEZ-ANO1(abc)-Lv105]
Yang, CH. et al. (2014) MicroRNA-21 promotes glioblastoma tumorigenesis by down-regulating insulin-like growth factor-binding protein-3 (IGFBP3).. The Journal of Biological Chemistry,. [IGFBP3 expression clone in pReceiver-lv105]

2013

Elmageed, ZY Abd. et al (2013) Neoplastic reprogramming of patient‐derived adipose stem cells by prostate cancer cell‐associated exosomes. Stem Cells, DOI: 10.1002/stem.1619. [lentivirus clones (pLV- eGFP)].
Kingsley, DM. et al (2013) Single-step laser-based fabrication and patterning of cell-encapsulated alginate microbeads. Biofabrication, Issue 4 (December 2013) doi:10.1088/1758-5082/5/4/045006. [mCherry crude lentiviral particle].
Radin, JN. et al (2013) Role of Connexin 43 in Helicobacter pylori VacA-induced cell death. Infection and Immunity, January 2014 vol. 82 no. 1 423-432. [lentivirus particles encoding human Cx43 and negative-control Lentifect lentivirus particles].
Almalki, A. et al (2013) Mutation of the human mitochondrial phenylalanine-tRNA synthetase causes infantile-onset epilepsy and cytochrome c oxidase deficiency. Biochimica et Biophysica Acta (BBA) – Molecular Basis of Disease, Volume 1842, Issue 1, January 2014, Pages 56–64. [Lentiviral particles containing wild-type FARS2 (LP-10240-Lv105-0200-S)].
Hoshino, A. et al (2013) A novel function for proSAAS as an amyloid anti‐aggregant in Alzheimer's disease. Journal of Neurochemistry, DOI: 10.1111/jnc.12454. [LP-U0612-Lv105-0200-S].
Cohen, CA. et al (2013) The Parity-Associated Microenvironmental Niche in the Omental Fat Band Is Refractory to Ovarian Cancer Metastasis. Cancer Prevention Research, Cancer Prev Res November 2013 6;1182. [Firefly luciferase (FFL) lentiviral particles].
Gilmour, AM. et al (2013) A novel epidermal growth factor receptor-signaling platform and its targeted translation in pancreatic cancer. Cellular Signalling, Volume 25, Issue 12, December 2013, Pages 2587–2603. [Lentifect™ lentiviral particles (LP-EGFP. LV105-0205)].
Ho, H. et al (2013) RhoJ modulates melanoma invasion by altering actin cytoskeletal dynamics. Pigment Cell & Melanoma Research, Volume 26, Issue 2, pages 218–225, March 2013. [RhoJ, pEZX-Lv105].
Su, H. et al (2013) Immediate expression of Cdh2 is essential for efficient neural differentiation of mouse induced pluripotent stem cells. Stem Cell Research, Volume 10, Issue 3, May 2013, Pages 338–348. [Nnat and Ptn, pReceiver-Lv156].
Kim, S.J. et al (2013) Regulation of dendritic cell activation by microRNA let-7c and BLIMP1. Journal of Clinical Investigation, 2013 February 1; 123(2): 823–833. [mouse Blimp1, lentivirus vector].
Zhu, S. et al (2013) Regulation of CXCR4-mediated invasion by DARPP-32 in gastric cancer cells. Molecular Cancer Research 11.1 (2013): 86-94. [Lentivirus expressing DARPP-32, short hairpin RNA (shRNA)-DARPP-32, or control shRNA].
Georges, S. et al (2013) A Disintegrin And Metalloproteinase 12 produced by tumour cells accelerates osteosarcoma tumour progression and associated osteolysis. European Journal of Cancer, online 13 March 2013. [Mouse ADAM12 gene and negative control, catalog#’s EX-Mm24235-Lv105, EX-EGFP-Lv105].
Shinojima, N. et al (2013) TGF-β Mediates Homing of Bone Marrow-Derived Human Mesenchymal Stem Cells to Glioma Stem Cells. Cancer research, doi: 10.1158/0008-5472.CAN-12-3086. [pEZ-Lv105-TGFβ].
Al-Zoubi, M. et al (2013) Creating a tumor-resistant microenvironment: Cell-mediated delivery of TNFα completely prevents breast cancer tumor formation in vivo. Cell Cycle, Volume 12, Issue 3 February 1, 2013. [Empty vector, TNFα, TNFR-1A, TNFR-1B; catalog#'s EX-NEG-Lv105, EX-A0276-Lv105, EX-Z2785-Lv105, EX-A0254-Lv105].
Kregel, S. et al (2013) Sox2 Is an Androgen Receptor-Repressed Gene That Promotes Castration-Resistant Prostate Cancer. PloS one, 8(1): e53701. doi:10.1371/journal.pone.0053701. [Lentiviral Sox2, AR, and Control vectors (pReceiver-Lv105)].
Hunter, K. et al (2013) Inherited variation in miR-290 expression suppresses breast cancer progression by targeting the metastasis susceptibility gene Arid4b. Cancer Research, doi: 10.1158/0008-5472.CAN-12-3513. [Lenti-Pac™ FIV Expression Packing Kit].
Hirata, H. et al (2013) MicroRNA-182-5p Promotes Cell Invasion and Proliferation by Down Regulating FOXF2, RECK and MTSS1 Genes in Human Prostate Cancer. PloS one, 8(1): e55502. doi:10.1371/journal.pone.0055502. [Lenti-Pac™ HIV Expression Packing Kit].
Zaid, T.M. et al (2013) Identification of FGFR4 as a Potential Therapeutic Target for Advanced-Stage, High-Grade Serous Ovarian Cancer. Clinical Cancer, February 15, 2013 19; 809. [FGFR4 lentiviral particles].
Sanchez-Alvarez, R. at al (2013) Mitochondrial dysfunction in breast cancer cells prevents tumor growth: Understanding chemoprevention with metformin. Cell Cycle, Volume 12, Issue 1, January 1, 2013 Pages 172-182. [Lentiviral plasmids, packaging cells and reagents].
Bam, R. et al (2013) Role of Bruton's tyrosine kinase (BTK) in myeloma cell migration and induction of bone disease. American Journal of Hematology, DOI: 10.1002/ajh.23433. [BTK lentiviral particles; catalog#’s LP-A0534-LV103, LP-EGFP-LV105-0200].
Siouda, M. et al. (2012) Transcriptional Regulation of the Human Tumor Suppressor DOK1 by E2F1. Molecular and Cellular Biology, December 2012 vol. 32 no. 23 4877-4890. [DOK1-shRNA in psiHIV-H1 vector].
Musick, J. et al. (2012) Induced Pluripotent Stem Cells and Related Methods. U.S. Patent No. 20,120,276,070. 1 Nov. 2012. [Lenti-Pac™ HIV Expression Packing Kit].
Amodio, N. et al. (2012) miR-29b sensitizes multiple myeloma cells to bortezomib-induced apoptosis through the activation of a feedback loop with the transcription factor Sp1. Cell Death and Disease, 3, e436; doi:10.1038/cddis.2012.175. [Lenti-Pac™ FIV Expression Packaging Kit].
Molejon, N. et al. (2012) MOLECULE PAGE. The Pancreapedia, Version 1.0, December 12, 2012, DOI: 10.3998/panc.2012.16. [Human BECN1 cDNA in pReceiver-Lv105 (LP-M0768-Lv105-0200-S)].
Martinez-Outschoorn, U. et al. (2012) BRCA1 mutations drive oxidative stress and glycolysis in the tumor microenvironment: Implications for breast cancer prevention with antioxidant therapies. Cell Cycle, Volume 11, Issue 23, December 1, 2012. [BRCA1 (EX-H0047-Lv105) and control (EX-NEG-Lv105)].
Hu, W. et al. (2012) Novel Function of NIBP in Breast Cancer. TEMPLE UNIV PHILADELPHIA PA. [NIBP-EGFP].
Goel, M. et al. (2012) Cochlin, Intraocular Pressure Regulation and Mechanosensing. PLoS ONE 7(4): e34309. doi:10.1371/journal.pone.0034309. [EX-Q0226-LV31, FPK-LvTR-20].
Danhauser, K. et al. (2012) < i> DHTKD1</i> Mutations Cause 2-Aminoadipic and 2-Oxoadipic Aciduria. American Journal of Human Genetics, Volume 91, Issue 6, 7 December 2012, Pages 1088-1094. [DHTKD1 (Product ID: H4610)].
Molejon, M. et al. (2012) Beclin 1. The Pancreapedia: Exocrine Pancreas Knowledge Base, DOI: 10.3998/panc.2012.16. [human BECN1 in pReceiver-Lv105].
Reyes, E. et al. (2012) Growth kinetics of CD133‐positive prostate cancer cells. The Prostate, DOI: 10.1002/pros.22616. [Lentiviral CD133, pReceiver-Lv105].
Capparelli, C. et al. (2012) Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis, via glycolysis and ketone production. Cell Cycle, Volume 11, Issue 12 June 15, 2012. [BNIP3, BNIP3L, Beclin1, CTSB, and ATG16L1, Lentiviral vectors].
Lee, S. et al. (2012) Nucleolar protein GLTSCR2 stabilizes p53 in response to ribosomal stresses. Cell Death and Differentiation (2012) 19, 1613–1622; doi:10.1038/cdd.2012.40; published online 20 April 2012. [Lentivector-based shRNA system].
Xie, Y. et al. (2012) MicroRNA-24 regulates XIAP to reduce the apoptosis threshold in cancer cells. Oncogene , (25 June 2012) | doi:10.1038/onc.2012.258. [XIAP, pReceiver-Lv19].
Capparelli, C. et al. (2012). CTGF drives autophagy, glycolysis, and senescence in cancer associated fibroblasts via HIF1 activation, metabolically promoting tumor growth. Cell Cycle Volume 11, Issue 12, June 15, 2012. [Lentiviral plasmids].
Simpfendorfer, K. et al. (2012) The autoimmunity-associated BLK haplotype exhibits cis-regulatory effects on mRNA and protein expression that are prominently observed in B cells early in development. Hum. Mol. Genet. (2012) 21 (17): 3918-3925. doi: 10.1093/hmg/dds220. [HIV Lenti-Pac].
Capparelli, C. et al. (2012) CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, “fueling” tumor growth via paracrine interactions, without an increase in neo-angiogenesis. Cell Cycle, Volume 11, Issue 19 October 1, 2012. [INK4A, ARF, WAF1/CIP1 lentiviral vectors].
Liu, S. et al. (2012) Loss of microRNA-205 expression is associated with melanoma progression. Laboratory Investigation 92, 1084-1096 (July 2012) | doi:10.1038/labinvest.2012.62. [eGFP lentiviral control].
Peng, D. et al. (2012) Glutathione peroxidase 7 protects against oxidative DNA damage in oesophageal cells. Gut 2012;61:1250-1260 doi:10.1136/gutjnl-2011-301078. [GPX7 shRNA lentiviral particles].
Fan, QM. et al. (2012) The CREB–Smad6–Runx2 axis contributes to the impaired osteogenesis potential of bone marrow stromal cells in fibrous dysplasia of bone. Journal of Pathology Volume 228, Issue 1, pages 45–55, September 2012. [lentivirus expression vector].
Pruitt, F. et al. (2012) Cathepsin D acts as an essential mediator to promote malignancy of benign prostatic epithelium. The Prostate online: 19 SEP 2012 DOI: 10.1002/pros.22589. [lentiviral transduction].
Li, J. et al. (2012) The Role of a Basolateral Transporter in Rosuvastatin Transport and its Interplay with Apical BCRP in Polarized Cell Monolayer Systems. DMD August 1, 2012 dmd.112.045666. [human ABCG2, pEZ-Lv151].
Xu, N. et al. (2012) FoxM1 mediated resistance to gefitinib in non-smallcell lung cancer cells. Acta Pharmacologica Sinica 33, 675-681 (May 2012) | doi:10.1038/aps.2011.188. [EX-Z5438-Lv135].
Yamamura, S. et al. (2012) MicroRNA-34a suppresses malignant transformation by targeting c-Myc transcriptional complexes in human renal cell carcinoma. Carcinogenesis (2012) 33 (2): 294-300. doi: 10.1093/carcin/bgr286 . [HIV Lenti-Pac].
Carito, V. et al. (2012) Metabolic remodeling of the tumor microenvironment: Migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth. Cell Cycle Volume 11, Issue 18 September 15, 2012. [human MSF, SMA, Rac1, cdc42].
Berry, D. et al. (2012) Transthyretin Blocks Retinol Uptake and Cell Signaling by the Holo-Retinol-Binding Protein Receptor STRA6. Mol. Cell. Biol. October 2012 vol. 32 no. 19 3851-3859. [Human STRA6].
Berry, D. et al. (2012) Cross talk between signaling and vitamin A transport by the retinol-binding protein receptor STRA6. Mol. Cell. Biol. 32 (15): 3164-3175. [Human STRA6].
Capozza, F. et al. (2012) Genetic Ablation of Cav1 Differentially Affects Melanoma Tumor Growth and Metastasis in Mice: Role of Cav1 in Shh Heterotypic Signaling and Transendothelial Migration. Cancer Res May 1, 2012 72; 2262 . [pReceiver-Lv105].
Lin, X. et al. (2012) miR-433 is aberrantly expressed in myeloproliferative neoplasms and suppresses hematopoietic cell growth and differentiation. Leukemia| doi:10.1038/leu.2012.224. [GBP2].
Yin, Z. et al. (2012) FTY720 Protects Cardiac Microvessels of Diabetes: A Critical Role of S1P1/3 in Diabetic Heart Disease. PLoS ONE 7(8): e42900. doi:10.1371/journal.pone.0042900. [PRKCB].
Salem, A. et al. (2012) Two-compartment tumor metabolism: Autophagy in the tumor microenvironment, and oxidative mitochondrial metabolism (OXPHOS) in cancer cells. Cell Cycle Volume 11, Issue 13 July 1, 2012 [lentiviral plasmids].
Kraskiewicz, H. et al. (2011) Partial XBP1 knockdown does not affect viability of oligodendrocyte precursor cells exposed to new models of hypoxia and ischemia in vitro. Journal of Neuroscience Research 5 (89): 661-673 [rat XBP1 shRNA lentivirus]
Nikkhah, M. et al. (2011) MCF10A and MDA-MB-231 human breast basal epithelial cell co-culture in silicon micro-arrays. Biomaterials 30 (32):7625-7632 [mCherry]
Zheng, L. et al. (2011) Tyrosine 23 Phosphorylation-Dependent Cell-Surface Localization of Annexin A2 Is Required for Invasion and Metastases of Pancreatic Cancer. PLoS ONE 4 (6) [mouse ANXA2 shRNA Lenti particle]
Pfisterer, U. et al. PNAS (2011) Direct conversion of human fibroblasts to dopaminergic neurons. 25 (108): 10343-10348; [ORFs for En1, Foxa2, Gli1, Lmx1a, Lmx1b, Msx1, Nurr1, Otx2, Pax2, and Pax5 in lentiviral vectors]
Gerards, M. et al. (2011) Riboflavin-responsive oxidative phosphorylation complex I deficiency caused by defective ACAD9: new function for an old gene. Brain 134 (1): 210-219. [Lenti ORF clone]
Danhauser, K. et al. (2011) Cellular rescue-assay aids verification of causative DNA-variants in mitochondrial complex I deficiency. Molecular Genetics and Metabolism, Volume 103, Issue 2. [FIV-based lentiviral cDNA].
Tano, N. et al. (2011) microRNA-150 regulates mobilization and migration of bone marrow-derived mononuclear cells by targeting Cxcr4. PLoS ONE 6(10): e23114. doi:10.1371/journal.pone.0023114. [Lenti-Pac™].
Haack, TB et al. (2010) Exome sequencing identifies ACAD9 mutations as a cause of complex I deficiency. Nature Genetics 42, 1131-1134, doi:10.1038/ng.706. [Lenti-Pac™ kit]
Strong Smooth Muscle Differentiation Is Dependent on Myocardin Gene Amplification in Most Human Retroperitoneal Leiomyosarcomas, Galle Pérot, Josette Derré, Jean-Michel Coindre, Franck Tirode, Carlo Lucchesi, Odette Mariani, Laure Gibault, Louis Guillou, Philippe Terrier and Alain Aurias, Cancer Research 69, 2269, March 15, 2009 [EX-E0450-Lv06]

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